Icariin, a distinguished prenylated flavonol glycoside extracted from various Epimedium species, commonly known as Horny Goat Weed or Yin Yang Huo, stands as a testament to nature's profound medicinal capabilities. With a CAS number of 489-32-7 and a molecular formula of C33H40O15, this remarkable compound has been a cornerstone in traditional Eastern medicine for centuries. NINGBO INNO PHARMCHEM CO.,LTD. specializes in the production of high-quality Icariin, leveraging advanced manufacturing processes to ensure purity and efficacy for diverse applications.

Historically, Icariin has been revered for its wide array of therapeutic benefits, ranging from enhancing male sexual function and supporting bone health, particularly in cases of osteoporosis, to alleviating symptoms of neurasthenia and improving cardiovascular well-being. Its traditional uses laid the groundwork for modern scientific inquiry, which continues to uncover the extensive pharmacological effects of this versatile compound.

Recent scientific studies have particularly highlighted Icariin's significant neuroprotective properties. It demonstrates remarkable potential in addressing various neurological and neuropsychiatric disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), cerebral ischemia (stroke), depression, and multiple sclerosis (MS). In the context of AD, Icariin has shown promise in improving cognitive deficits and memory function, partly by reducing amyloid-beta (Aβ) deposition and influencing key signaling pathways that combat neuronal degeneration. For PD, research indicates its ability to protect dopaminergic neurons, mitigating neuronal loss and reducing neuroinflammation, which is a critical factor in disease progression.

Furthermore, Icariin exhibits profound benefits in mood regulation. It has been observed to alleviate depression-like behaviors in animal models, influencing neurogenesis in the hippocampus and modulating the hypothalamic-pituitary-adrenal (HPA) axis, which plays a central role in stress response. Its efficacy in mitigating brain injury following cerebral ischemia and stroke is attributed to its ability to prevent neuronal damage and reduce inflammation. In MS, Icariin supports myelin regeneration and exerts anti-inflammatory effects by modulating immune responses and central nervous system inflammatory pathways.

The anti-aging potential of Icariin is another area of intense research. Studies suggest that it can delay cellular senescence and improve cognitive function in aged models, contributing to a healthier lifespan. This multifaceted action is largely mediated by its powerful antioxidant and anti-inflammatory properties, coupled with its ability to promote neurogenesis and regulate crucial cellular pathways involved in energy metabolism and cellular repair, such as SIRTs and AMPK/mTOR/ULK1 pathways. Icariin's capacity to combat oxidative stress and neuronal apoptosis further underscores its broad therapeutic scope.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a reliable manufacturer and supplier of premium Icariin. Our dedication to stringent quality control and Good Manufacturing Practices (GMP) ensures that our product meets the highest industry standards. For those looking to buy Icariin or seeking information on Icariin price and bulk purchase options, our team is readily available to provide detailed product specifications and competitive quotations. We pride ourselves on offering a product that supports advanced research and development in pharmaceuticals and nutraceuticals, ensuring both purity and consistent supply for our global partners.