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Mitoxantrone Hydrochloride, identified by CAS number 70476-82-3, is a potent active pharmaceutical ingredient (API) that plays a crucial role in modern medicine. As a synthetic anthracenedione derivative, this dark blue or reddish powder is a cornerstone in the formulation of treatments for several aggressive diseases. Its development marked a significant advancement in chemotherapy, offering a powerful therapeutic option with a distinct mechanism of action.
The primary application of Mitoxantrone Hydrochloride is in oncology. It is a well-established antineoplastic agent used to combat various forms of cancer. Clinically, it is approved for treating metastatic breast cancer, acute non-lymphocytic leukemia (ANLL), and advanced hormone-refractory prostate cancer. Its effectiveness stems from its ability to interfere with the genetic material of cancer cells. By intercalating into DNA and inhibiting a critical enzyme known as topoisomerase II, Mitoxantrone Hydrochloride effectively disrupts DNA replication and repair processes. This action leads to DNA strand breaks and ultimately induces apoptosis (programmed cell death) in rapidly dividing cancer cells, thereby slowing or halting tumor growth.
Beyond its use in cancer therapy, Mitoxantrone Hydrochloride has also found a significant role as an immunosuppressive agent. It is approved for treating certain forms of multiple sclerosis (MS), including secondary progressive, progressive-relapsing, and worsening relapsing-remitting MS. In these autoimmune conditions, the body's immune system mistakenly attacks the central nervous system. Mitoxantrone works by suppressing the activity of key immune cells like T-cells, B-cells, and macrophages, which reduces the inflammation and nerve damage characteristic of MS, helping to slow disease progression and reduce the frequency of relapses.
The quality and purity of this API are paramount to ensure the safety and efficacy of the final drug formulations. At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in the production of high-grade Mitoxantrone Hydrochloride powder that meets stringent pharmaceutical standards. Our manufacturing processes are meticulously controlled to produce a product with high purity and consistency, ensuring it is suitable for the most demanding therapeutic applications.
As the demand for advanced cancer and MS treatments grows, securing a reliable source for this critical raw material is essential for pharmaceutical developers. For companies looking to develop or manufacture these life-saving therapies, partnering with a trusted manufacturer is the first step. NINGBO INNO PHARMCHEM CO.,LTD. stands as a leading supplier in the market, committed to excellence and quality. If you are looking to buy or purchase Mitoxantrone Hydrochloride, we offer competitive price points without compromising on the integrity of our product. We encourage you to reach out to explore how our high-quality API can fit into your production pipeline.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
