In the realm of effective antimicrobial agents, Poly(hexamethylenebiguanide)hydrochloride, commonly known as PHMB, stands out as a highly versatile and potent compound. Identified by its primary CAS Number 27083-27-8, PHMB is a polymer celebrated for its exceptional broad-spectrum antimicrobial and antifungal activity. It is available in various forms to suit diverse industrial needs, including a high-quality PHMB powder and a convenient PHMB 20% liquid solution.

PHMB functions as a cationic disinfectant. Its mechanism of action is rooted in its electrostatic interaction with negatively charged components of microbial cell membranes, such as the lipopolysaccharide layer in Gram-negative bacteria. This interaction disrupts the membrane integrity, leading to cellular leakage and ultimately the death of the microorganism. This distinct mode of action contributes to its effectiveness against a wide range of pathogens.

The efficacy of PHMB is well-documented against numerous problematic microorganisms. This includes significant bacterial strains like Pseudomonas aeruginosa, Staphylococcus aureus (including the challenging methicillin-resistant MRSA), Escherichia coli, vancomycin-resistant enterococci, and Klebsiella pneumoniae. Furthermore, PHMB is effective against fungi, including the yeast Candida albicans and the mold Aspergillus brasiliensis. Its ability to tackle such a diverse array of microbes makes it an invaluable asset in hygiene and sterilization protocols.

The applications for PHMB are extensive and varied. Due to its antiseptic and disinfectant properties, it is widely used in healthcare settings for wound management and skin disinfection. It is also an important ingredient in certain multipurpose contact lens solutions, providing necessary disinfection to prevent microbial contamination. Beyond medical and personal care, PHMB is utilized in water treatment, textile finishing, and as a general surface disinfectant across various industries. Its stability, low odor, and effectiveness at relatively low concentrations make it a preferred choice over many traditional disinfectants.

Supplying PHMB in both powder and 20% liquid forms allows for flexibility in formulation and application. The powder form offers ease of storage and transportation for certain uses, while the liquid solution provides ready-to-use convenience for others. Both forms maintain the intrinsic powerful antimicrobial properties of the poly(hexamethylenebiguanide) polymer. Packaging options typically include robust drums and bags designed to protect product integrity during transit and storage.

For businesses seeking a reliable source of this essential antimicrobial polymer, finding a trustworthy PHMB manufacturer or PHMB supplier is crucial. Quality and consistency are paramount when dealing with active pharmaceutical ingredients and disinfectants. Prospective buyers often inquire about the PHMB price, which can vary based on concentration, form, packaging, and order volume. To buy PHMB or purchase PHMB effectively, understanding the specific requirements of your application and sourcing from experienced suppliers is recommended. Reliable suppliers can provide detailed specifications, safety data sheets, and technical support to ensure the product meets your stringent requirements.