N-Ethyl-N-methylcarbamoyl Chloride, identified by its CAS Registry Number 42252-34-6, stands as a critical chemical intermediate in the pharmaceutical industry. Also known by its synonym N-ethyl-N-methylcarbamoylchloride, this compound plays a pivotal role in the synthesis of complex active pharmaceutical ingredients (APIs). Its molecular formula is C4H8ClNO, and it has a molecular weight of 121.57 g/mol, making it a moderately sized, yet highly reactive, organic compound.

As a colorless liquid, N-Ethyl-N-methylcarbamoyl Chloride exhibits distinct physical and chemical properties that are crucial for its industrial application. It has a density of approximately 1.101 g/cm3. The boiling point is noted at 165.1ºC at 760 mmHg, indicating its volatility under standard conditions. Its flash point is 53.7ºC, highlighting the need for careful handling and storage due to its flammable nature. The refractive index, measured at 1.441, further characterizes this substance, allowing for its identification and quality assurance through optical methods.

Quality and purity are paramount for pharmaceutical intermediates. N-Ethyl-N-methylcarbamoyl Chloride is typically supplied with a high purity level, usually equal to or greater than 98%. Rigorous analytical methods are employed to ensure minimal total impurities, generally kept below 1.50%. This adherence to strict specifications ensures its suitability for sensitive pharmaceutical synthesis processes, where even trace impurities can impact the final product's efficacy and safety. Its colorless liquid appearance is another key indicator of its high quality.

The primary and most significant application of N-Ethyl-N-methylcarbamoyl Chloride is its use as a vital intermediate in the synthesis of Rivastigmine (CAS: 123441-03-2) and its tartrate salt, Rivastigmine tartrate (CAS: 129101-54-8). Rivastigmine is an acetylcholinesterase inhibitor, a class of medication primarily used for the symptomatic treatment of mild to moderate Alzheimer's disease and Parkinson's disease dementia. Its role in these therapeutic applications underscores the importance of a reliable supply of N-Ethyl-N-methylcarbamoyl Chloride. The precision required in synthesizing such medications demands an intermediate of unwavering consistency and purity.

For packaging, N-Ethyl-N-methylcarbamoyl Chloride is commonly supplied in 25kg cardboard drums, though packaging can be customized to meet specific customer requirements. Proper storage is essential to maintain its integrity and reactivity. It should be stored in a cool and dry well-closed container, away from moisture and strong light or heat. Maintaining temperatures between 2°C and 8°C, and potentially under a nitrogen blanket to prevent degradation, are often recommended practices to ensure product longevity and stability.

As a leading supplier and manufacturer of specialty chemicals and pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality N-Ethyl-N-methylcarbamoyl Chloride. We understand the critical demand for reliable chemical building blocks in the pharmaceutical and research sectors. Our commitment to quality ensures that our product meets the stringent requirements for synthesizing Rivastigmine and other complex organic compounds. For competitive price inquiries, to buy N-Ethyl-N-methylcarbamoyl Chloride, or to discuss bulk purchase options, please reach out to our sales team. We strive to be your preferred chemical supplier, offering seamless procurement processes and comprehensive support for your chemical needs.