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N,N'-Di-tert-butoxycarbonyl-L-histidine: A Key Intermediate for Pharmaceutical Building Blocks

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying the pharmaceutical industry with high-quality chemical intermediates that form the backbone of drug development. N,N'-Di-tert-butoxycarbonyl-L-histidine, identified by CAS number 20866-46-0, is one such crucial intermediate. This derivative of the essential amino acid histidine is indispensable for constructing complex pharmaceutical building blocks due to its protected functional groups and unique chemical properties.

The pharmaceutical industry relies heavily on precise chemical synthesis to create active pharmaceutical ingredients (APIs) and their precursors. Histidine, with its imidazole ring, plays a significant role in various biological functions and is often incorporated into therapeutic peptides and small molecules. However, its reactivity necessitates protective strategies during synthesis. N,N'-Di-tert-butoxycarbonyl-L-histidine provides a robust solution by shielding both the alpha-amino group and the imidazole nitrogen with tert-butoxycarbonyl (Boc) groups. These Boc groups are stable under many reaction conditions but can be readily cleaved when needed, allowing for sequential addition and modification of the histidine residue within a larger molecular structure.

Our commitment at NINGBO INNO PHARMCHEM CO.,LTD. ensures that the N,N'-Di-tert-butoxycarbonyl-L-histidine we supply meets the stringent purity and quality standards required by the pharmaceutical sector. This high level of quality control is vital for ensuring the efficacy and safety of the final drug products derived from these intermediates. Researchers developing new peptide-based drugs, enzyme inhibitors, or other biologically active compounds find this protected histidine derivative to be an invaluable tool for achieving their synthetic goals.

By providing access to critical pharmaceutical building blocks like N,N'-Di-tert-butoxycarbonyl-L-histidine, NINGBO INNO PHARMCHEM CO.,LTD. supports the innovation pipeline of the pharmaceutical industry. We enable scientists to efficiently synthesize complex molecules, accelerating the discovery and development of new medicines. Explore how our commitment to quality and our comprehensive range of intermediates can benefit your pharmaceutical research and manufacturing processes.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
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