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NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing advanced chemical intermediates that are fundamental to modern synthetic chemistry. Among these, amino acid derivatives with protective groups are of paramount importance, particularly for complex multi-step syntheses. N,N'-Di-tert-butoxycarbonyl-L-histidine (CAS 20866-46-0) exemplifies the critical role of tert-butoxycarbonyl (Boc) protection in manipulating amino acids like histidine.
The Boc group is a widely used protecting group in organic chemistry, especially in peptide synthesis. Its popularity stems from its stability under a variety of reaction conditions (e.g., basic conditions, hydrogenation, catalytic reduction) and its facile removal under mild acidic conditions (e.g., trifluoroacetic acid). For histidine, which possesses both an amino group and an imidazole ring that can participate in unwanted side reactions, dual Boc protection, as seen in N,N'-Di-tert-butoxycarbonyl-L-histidine, offers enhanced control. This dual protection allows chemists to selectively activate and react specific parts of the molecule, thereby preventing epimerization and other side reactions that can compromise the yield and purity of the final product.
Our supply of N,N'-Di-tert-butoxycarbonyl-L-histidine, with its guaranteed high purity, ensures that researchers and manufacturers can rely on consistent performance. This reliability is essential when working with sensitive substrates or synthesizing high-value compounds for pharmaceutical or biotechnology applications. By using N,N'-Di-tert-butoxycarbonyl-L-histidine, scientists can confidently incorporate histidine into peptide chains or utilize it as a scaffold for developing novel chemical entities, knowing that the protection strategy is robust and well-established.
As the demand for sophisticated peptide-based drugs and biomaterials grows, so does the need for high-quality, protected amino acids. NINGBO INNO PHARMCHEM CO.,LTD. remains at the forefront, providing essential reagents like N,N'-Di-tert-butoxycarbonyl-L-histidine to facilitate these cutting-edge research efforts. Partner with us to access the reliable chemical intermediates you need to drive innovation in your synthetic chemistry endeavors.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
