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Nicotinamide N-oxide, identified by its CAS number 1986-81-8, is a compound that holds significant value within the scientific research community. Its unique chemical structure and biological activity make it an indispensable tool for investigations in various fields, from biochemistry to pharmacology. Understanding its properties is the first step for any researcher looking to leverage its potential.
Chemically, Nicotinamide N-oxide is characterized by its molecular formula C6H6N2O2 and a molecular weight of approximately 138.12 g/mol. It typically presents as a white powder, with a melting point that often indicates decomposition around 291-293 °C. These physical properties are vital for handling, storage, and formulation. Sourcing this compound from a reputable manufacturer, especially one offering high purity (e.g., 97%+), is crucial for obtaining accurate and reproducible research results.
Biologically, Nicotinamide N-oxide is known for two primary roles. Firstly, it is an in vivo metabolite of nicotinamide, a key B vitamin. This makes it relevant for studies focused on niacin metabolism, cellular energy pathways, and the biochemical fate of Vitamin B3 within organisms. Researchers investigating metabolic disorders or the impact of dietary supplements may find this compound essential for their work.
Secondly, Nicotinamide N-oxide acts as a potent antagonist of the CXCR2 receptor. This receptor is a critical component of the immune system, particularly in regulating neutrophil migration during inflammatory processes. As such, Nicotinamide N-oxide is frequently used in research related to inflammation, immunology, and the development of novel anti-inflammatory agents. Its ability to selectively target CXCR2 provides a precise mechanism for studying and modulating inflammatory responses.
For researchers needing to buy Nicotinamide N-oxide, identifying reliable suppliers is key. Many specialized chemical companies, including those operating as a chemical manufacturer in China, offer this compound. When you purchase, always look for detailed product specifications and inquire about pricing and availability. Requesting a quote from a trusted vendor ensures you receive accurate information and competitive rates. The strategic sourcing of high-quality Nicotinamide N-oxide is a foundational step for successful research outcomes in its diverse application areas.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
