Nicotinamide N-oxide (CAS 1986-81-8) is a molecule of considerable interest for its multifaceted roles in biological research. Its significance spans two key areas: as a metabolite involved in nutrient processing and as a modulator of inflammatory responses. For researchers in these fields, understanding the properties and availability of this compound is crucial for advancing scientific inquiry.

In the realm of metabolism, Nicotinamide N-oxide is recognized as an in vivo metabolic product of nicotinamide, a vital form of Vitamin B3. Nicotinamide is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme fundamental to energy production and cellular health. The formation of Nicotinamide N-oxide represents a pathway in the body's processing of nicotinamide. Researchers studying nutritional biochemistry, the effects of dietary intake, or specific metabolic disorders may find Nicotinamide N-oxide an important compound for investigating these processes. Its presence and levels can serve as indicators in certain physiological states.

Equally significant is the role of Nicotinamide N-oxide as a selective antagonist of the CXCR2 receptor. CXCR2 is integral to the inflammatory cascade, particularly its role in the migration of neutrophils to sites of inflammation. By blocking CXCR2, Nicotinamide N-oxide can help to modulate inflammatory reactions. This makes it a valuable tool for scientists investigating autoimmune diseases, acute and chronic inflammatory conditions, and the body's response to infection or injury. The ability to precisely target this receptor pathway offers potential for developing novel anti-inflammatory therapeutics.

For those looking to acquire Nicotinamide N-oxide for their research, finding a reliable supplier or manufacturer is essential. Companies that specialize in high-purity fine chemicals, often based in regions like China, provide competitive pricing and ensure product quality. When you need to buy this compound, looking for its CAS number (1986-81-8) is the first step. A reputable chemical manufacturer will offer detailed specifications, including purity (typically 97%+) and physical characteristics. It's always recommended to request a quote to confirm availability and cost, especially for research quantities or potential scale-up.

The diverse applications of Nicotinamide N-oxide underscore its importance in modern scientific research. Whether delving into the complexities of human metabolism or exploring the mechanisms of inflammation, this chemical provides researchers with a powerful tool. By partnering with trusted chemical providers, scientists can ensure they have access to the high-quality Nicotinamide N-oxide needed to drive their discoveries forward.