In the evolving landscape of advanced skincare and cosmetic formulation, Nonapeptide-1 stands out as a revolutionary ingredient. Developed by NINGBO INNO PHARMCHEM CO.,LTD., this sophisticated peptide offers a targeted approach to achieving a brighter, more even, and youthful complexion. As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures the highest quality of this potent compound for global distribution, catering to the growing demands of the cosmetic industry.

Nonapeptide-1, also known as Melanostatine or by its full chemical sequence H-Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2, is a synthetic nonapeptide. Identified by the CAS No. 158563-45-2, its molecular formula is C61H87N15O9S with a molecular weight of 1206.504. Appearing as a fine white powder, Nonapeptide-1 consistently meets stringent quality standards, typically boasting an assay of ≥98.0%. This high purity is critical for its efficacy in skincare applications, ensuring reliable and consistent performance in final product formulations.

The remarkable ability of Nonapeptide-1 to control skin tone and reduce unwanted pigmentation lies in its unique mechanism of action. It functions as a biomimetic peptide and a specific antagonist of the alpha-melanocyte-stimulating hormone (α-MSH). In the skin, α-MSH binds to the Melanocortin 1 Receptor (MC1-R) on melanocytes, triggering a cascade of events that ultimately leads to the activation of tyrosinase, the key enzyme responsible for melanin synthesis. Nonapeptide-1 effectively competes with α-MSH for binding to the MC1-R. By occupying this receptor, it prevents the activation of tyrosinase, thereby blocking the melanin synthesis pathway at an early stage. This competitive inhibition significantly reduces the formation of new melanin, leading to a visible reduction in hyperpigmentation and an improvement in overall skin clarity.

The applications of Nonapeptide-1 extend far beyond simple skin lightening. Its primary benefit is its powerful effect on reducing hyperpigmentation, including dark spots, age spots, and melasma, by inhibiting melanin production. This leads to a more uniform and radiant skin tone. Furthermore, research indicates that Nonapeptide-1 may possess anti-inflammatory properties, which are crucial in combating skin aging by preventing collagen breakdown and the formation of fine lines and wrinkles. By reducing inflammation, it helps promote healthier, more youthful-looking skin. Some studies also suggest its potential to improve skin hydration by stimulating natural moisturizing factors, which keeps the skin plump and further reduces the appearance of fine lines. Its versatile nature makes it an ideal ingredient for a wide array of cosmetic formulations, including emulsions, gels, essences, and specialized eye creams targeting pigmentation concerns.

As a dedicated manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. adheres to rigorous quality control protocols, ensuring that every batch of Nonapeptide-1 meets the highest industry standards. Our product is typically packaged in quantities such as 5 kg drums, with flexibility to accommodate diverse customer requirements. For optimal preservation of its efficacy, Nonapeptide-1 should be stored in a cool, ventilated place, ideally at or below -20°C in its lyophilized form, ensuring its stability and longevity. When it comes to sourcing this advanced ingredient, NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable supplier offering competitive price options for both small and large-scale orders. Companies looking to buy or purchase high-quality Nonapeptide-1 for their cosmetic lines are encouraged to reach out to inquire about our comprehensive supply solutions. We pride ourselves on facilitating a seamless procurement process for our global clientele, ensuring timely delivery and exceptional product integrity for your advanced skincare formulations.