NINGBO INNO PHARMCHEM CO.,LTD. is proud to present its premium Pharmaceutical Grade Indomethacin, a cornerstone active pharmaceutical ingredient (API) widely recognized for its potent anti-inflammatory, analgesic, and antipyretic properties. Identified by CAS No. 53-86-1, this crystalline powder is a critical raw material for various pharmaceutical formulations globally. Our commitment to excellence ensures that every batch of Indomethacin meets the most stringent quality standards, providing unparalleled purity and efficacy for our clients.

Indomethacin, with the chemical formula C19H16ClNO4 and a molecular weight of 357.79, is supplied as a fine crystalline powder. It exhibits a melting point typically between 158-162 °C and is soluble in ethanol at 50 mg/mL, forming a clear, yellow-green solution. The primary mechanism of action for Indomethacin involves the inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes. This inhibition significantly reduces the synthesis of prostaglandins, which are key mediators of pain, inflammation, and fever in the body. By targeting these pathways, Indomethacin effectively alleviates symptoms associated with various inflammatory conditions.

The versatile nature of Indomethacin makes it indispensable across a spectrum of therapeutic areas. It is extensively used in the symptomatic treatment of moderate to severe rheumatoid arthritis, where it helps in relieving pain and stiffness, reducing swelling, and improving joint mobility. Similarly, it is highly effective in managing osteoarthritis, a condition characterized by joint inflammation due to cartilage breakdown, and ankylosing spondylitis, an autoimmune condition affecting spinal joints. Indomethacin is also a preferred choice for treating acute gouty arthritis, providing rapid relief from severe pain and swelling. Beyond chronic conditions, it addresses acute painful shoulder conditions such as bursitis and tendinitis. Its applications extend to more specialized uses, including the treatment of patent ductus arteriosus (PDA) in premature neonates, the prevention of pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP), and as a tocolytic agent for inhibiting uterine contractions in preterm labor.

At NINGBO INNO PHARMCHEM CO.,LTD., we prioritize the production of Indomethacin with a purity exceeding 99%. Our manufacturing processes adhere strictly to international pharmaceutical standards, including GMP (Good Manufacturing Practice), ISO 9001, and critical pharmacopoeial standards such as USP (United States Pharmacopeia) and BP (British Pharmacopoeia). Each batch undergoes rigorous testing, typically via HPLC UV, to confirm its identity, purity, and potency. We ensure proper storage conditions in a cool, dry place, providing a shelf life of two years, thereby guaranteeing the stability and integrity of the product until its use. This meticulous approach to quality assurance underscores our dedication to providing APIs that healthcare professionals can trust.

As a leading manufacturer and supplier of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting the diverse needs of the global pharmaceutical industry. We offer highly competitive price points for bulk orders of Indomethacin, making it an economically viable choice without compromising on quality. For those looking to buy or purchase Indomethacin, our streamlined process ensures efficient order fulfillment and reliable delivery. Our extensive production capacity and robust supply chain allow us to handle significant volumes, ensuring consistent availability for your manufacturing requirements. We invite pharmaceutical companies worldwide to explore a partnership with us for their Indomethacin needs, confident in our ability to provide superior product quality and dedicated service.