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Direct compression (DC) tableting is a highly efficient manufacturing process that relies on excipients with superior compressibility and flow properties. Among these, Microcrystalline Cellulose (MCC) is paramount, offering a unique combination of attributes that make it the excipient of choice for many formulations. NINGBO INNO PHARMCHEM CO.,LTD. explores the science behind MCC’s success in direct compression.
The core principle of direct compression is to blend the active pharmaceutical ingredient (API) with excipients and then compress this blend directly into tablets without prior granulation. For this process to be successful, the excipients must possess excellent flowability to ensure consistent die filling and high compressibility to form robust tablets. MCC excels in both these areas. Its particle structure allows for plastic deformation under pressure, creating strong inter-particle bonds and yielding tablets with high tensile strength and low friability. When you buy microcrystalline cellulose for DC, you are investing in a material that inherently supports this efficient manufacturing method.
As a microcrystalline cellulose binder, MCC is unparalleled in direct compression. It can effectively bind APIs and other excipients, even those with poor tableting characteristics. This binding ability is crucial for producing tablets that can withstand handling and transport. The plastic deformation mechanism of MCC contributes to the formation of a strong tablet network. This contrasts with brittle excipients that fracture under pressure, leading to weaker compacts.
Furthermore, MCC acts as an excellent filler and contributes to the overall bulk of the tablet, ensuring accurate dosing. Its inert nature means it does not typically react with APIs, preserving the stability of the final drug product. The ability to achieve high tablet hardness with MCC at low compression forces also reduces stress on tableting machinery, leading to lower maintenance costs and increased operational efficiency.
NINGBO INNO PHARMCHEM CO.,LTD. understands that the quality of the microcrystalline cellulose pharmaceutical grade product directly impacts the success of direct compression formulations. We provide MCC with consistent physical properties, ensuring reliable performance. Whether you are developing immediate-release tablets or more complex dosage forms, choosing the right MCC grade from NINGBO INNO PHARMCHEM CO.,LTD. can significantly enhance your manufacturing efficiency and product quality. Our commitment is to supply reliable microcrystalline cellulose that drives innovation in pharmaceutical manufacturing.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
