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Wet granulation is a widely used technique in pharmaceutical manufacturing to improve the flow and compressibility of powder blends, especially for APIs that do not lend themselves to direct compression. Microcrystalline Cellulose (MCC) is an exceptional excipient for wet granulation, offering numerous benefits that enhance both the process and the final tablet properties. NINGBO INNO PHARMCHEM CO.,LTD. highlights the advantages of incorporating MCC into wet granulation processes.
The efficacy of MCC in wet granulation stems from its unique physical characteristics. Its porous structure and high surface area allow it to absorb granulating fluid efficiently, acting as a 'wicking agent'. This ensures even distribution of the liquid throughout the powder blend, leading to more uniform granule formation. Furthermore, MCC's ability to retain water helps to prevent over-wetting, a common issue that can lead to processing difficulties and affect granule quality. This controlled moisture management is key to achieving consistent results when you buy microcrystalline cellulose for wet granulation.
As a microcrystalline cellulose binder in wet granulation, MCC promotes the formation of strong, robust granules. During the granulation process, MCC particles help to create effective bonds within the granules, which translate into tablets with good hardness and low friability. This improved mechanical strength is crucial for tablets that need to withstand handling and packaging without breaking.
Moreover, the use of MCC in wet granulation can also contribute to its role as a microcrystalline cellulose disintegrant. While the granulation process itself can affect disintegration properties, MCC generally maintains its ability to swell and aid tablet breakup, ensuring the timely release of the API. The combination of binding and disintegration properties makes MCC a highly versatile excipient for this process.
NINGBO INNO PHARMCHEM CO.,LTD. provides premium microcrystalline cellulose pharmaceutical grade products that are optimized for wet granulation. Our MCC grades ensure excellent wetting properties, improved drying efficiency, and enhanced granule uniformity. By choosing NINGBO INNO PHARMCHEM CO.,LTD., manufacturers can confidently incorporate MCC into their wet granulation processes to achieve superior tablet quality and manufacturing efficiency. Sourcing high-quality microcrystalline cellulose is a strategic decision for pharmaceutical success.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
