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Povidone K90 (PVP K90) is a widely recognized and utilized polymer in the pharmaceutical industry, valued for its unique combination of physical and chemical properties, as well as its favorable safety profile. This water-soluble polymer, a grade of polyvinylpyrrolidone, plays a crucial role as an excipient in numerous drug formulations.
Chemically, Povidone K90 is a synthetic polymer derived from N-vinyl-2-pyrrolidone. It is characterized by its high molecular weight, which contributes to its excellent binding and film-forming capabilities. As a white to slightly yellow amorphous powder, it is highly soluble in water and various organic solvents, making it adaptable to diverse manufacturing processes. Its non-ionic nature ensures compatibility with a wide range of active pharmaceutical ingredients (APIs) and other excipients, minimizing the risk of unwanted interactions.
The functional properties of PVP K90 are extensive. It serves as an effective binder in tablet manufacturing, providing the necessary cohesion for tablet integrity. Its film-forming ability is utilized in tablet coatings, offering protection and improving the aesthetic qualities of dosage forms. Furthermore, its capacity to enhance drug solubility makes it invaluable for improving the bioavailability of poorly soluble compounds.
From a safety perspective, Povidone K90 is generally considered safe for pharmaceutical use. It has been extensively studied and is approved by regulatory bodies like the U.S. Food and Drug Administration (FDA), often recognized as Generally Recognized As Safe (GRAS). When administered orally, it is poorly absorbed from the gastrointestinal tract and is largely excreted unchanged, contributing to its low systemic toxicity. While allergic reactions are rare, they have been documented, particularly with specific administration routes or in conjunction with other substances. Pharmaceutical-grade Povidone K90 from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures adherence to rigorous quality and purity standards, further reinforcing its safety in medical applications.
The versatility, efficacy, and safety of Povidone K90 solidify its position as a critical excipient in the pharmaceutical industry, enabling the development of stable, effective, and patient-friendly drug products.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
