High-Sensitivity Voltage-Sensitive Dye for Advanced Electrophysiology Research | Manufacturer & Supplier
Discover ANNINE-6plus, a state-of-the-art voltage-sensitive dye enabling unparalleled optical voltage imaging. As a leading supplier, we provide this essential tool for researchers in neuroscience and cardiac electrophysiology, offering superior sensitivity and temporal resolution. Contact us for a quote.
Get a Quote & SampleLeading Optical Voltage Imaging Capabilities
ANNINE-6plus
ANNINE-6plus is a cutting-edge, water-soluble voltage-sensitive dye crucial for optical measurement of transmembrane voltage in excitable cells. Our manufacturing ensures high purity and consistent performance, making us a reliable supplier for your research needs. Benefit from its enhanced water solubility and strong membrane binding, ideal for precise electrophysiology applications. Purchase this advanced reagent from our China-based facility for competitive pricing and stable supply.
- High Voltage Sensitivity: Achieve detailed neuronal activity monitoring with 30-50% ΔF/F per 100 mV sensitivity, crucial for detecting subtle voltage changes.
- Nanosecond Response Time: Capture ultrafast neuronal events with exceptional temporal resolution, enabling precise analysis of action potentials.
- Improved Water Solubility: Easily prepare samples without organic solvents, facilitating direct cell staining for various electrophysiology research applications.
- Minimal Phototoxicity & Bleaching: Conduct prolonged imaging sessions without damaging cells, ensuring reliable data acquisition for in vivo studies.
Key Advantages for Your Research
Superior Signal-to-Noise Ratio
Optimize your voltage imaging experiments with ANNINE-6plus. Its inherent sensitivity and compatibility with two-photon microscopy significantly enhance the signal-to-noise ratio, allowing for clear detection of both supra- and sub-threshold voltage changes.
Versatile Application Protocols
As a leading manufacturer, we ensure our voltage-sensitive dye supports diverse experimental setups. It's ideal for bulk loading in vivo or internal cell loading via electroporation, enabling comprehensive neuronal and cardiac electrophysiology studies.
Electrochromic Mechanism for Linear Response
Experience a direct and linear response to membrane potential changes due to its purely electrochromic nature. This simplifies quantitative analysis and provides reliable data for buy-side decisions on research materials.
Applications in Electrophysiology
Neuronal Activity Monitoring
Precisely track membrane potential changes in neurons for in-depth analysis of action potentials and synaptic integration. Purchase ANNINE-6plus for reliable neuronal signaling research.
Cardiac Electrophysiology
Investigate action potential propagation and t-tubule voltage dynamics in cardiomyocytes. Our dye is a key reagent for cardiac researchers seeking to buy high-performance optical probes.
In Vivo Voltage Imaging
Perform depth-resolved imaging in scattering tissues with two-photon microscopy, allowing for the study of brain activity in awake, behaving animals. Source your essential reagents from us.
Simultaneous Imaging
Combine with calcium indicators for simultaneous measurement of voltage and calcium dynamics, providing a comprehensive understanding of cellular signaling. Inquire about bulk pricing for this synergistic application.