1,1'-Oxalyldiimidazole: A Versatile Coupling Reagent for Peptide Synthesis and Beyond

Discover the power of 1,1'-Oxalyldiimidazole, a key reagent in modern peptide synthesis. Explore its efficiency in forming peptide bonds and its broader applications in organic chemistry and beyond. Learn why it's a preferred choice for researchers and manufacturers.

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Advantages Offered

Minimized Racemization

The use of 1,1'-Oxalyldiimidazole as a peptide coupling reagent significantly minimizes racemization, a critical factor in producing chirally pure peptides for pharmaceutical development.

Broad Applicability in Organic Synthesis

This versatile compound is instrumental in a wide array of organic synthesis reactions, acting as a powerful tool for chemists in diverse research and development settings.

Facilitates Complex Molecule Construction

By enabling efficient amide bond formation, 1,1'-Oxalyldiimidazole aids in the construction of complex organic molecules, supporting advancements in material science and drug discovery.

Key Applications

Peptide Synthesis

1,1'-Oxalyldiimidazole is a cornerstone in solid-phase and solution-phase peptide synthesis, ensuring efficient coupling for therapeutic peptides and research biomolecules.

Coordination Chemistry

Its ability to form stable complexes with metal ions makes it a valuable ligand in coordination chemistry for catalysis and material design.

Pharmaceutical Manufacturing

As a critical intermediate, it supports the synthesis of active pharmaceutical ingredients (APIs), contributing to novel drug development.

Agrochemical Development

The compound finds use in creating agrochemicals, leveraging its chemical properties for the development of crop protection agents.