3-Bromo-2-fluorobenzonitrile: A Versatile Intermediate for Pharmaceutical and Material Synthesis
Unlock new possibilities in drug discovery and material science with this key organic building block.
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3-Bromo-2-fluorobenzonitrile
3-Bromo-2-fluorobenzonitrile (CAS: 840481-82-5) is a vital chemical intermediate with the molecular formula C7H3BrFN and a molecular weight of 200.01. It is characterized by its very faint orange crystalline powder appearance, a melting point typically between 37-40°C, and a density around 1.69±0.1 g/cm³. This compound is highly valued for its role as a foundational building block in complex organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs), specialized dyes, and advanced electronic materials like those used in OLEDs.
- Leverage its utility as a fluorinated benzonitrile building block for drug discovery and medicinal chemistry. This chemical intermediate enables the synthesis of novel therapeutic compounds.
- Utilize palladium-catalyzed cross-coupling reactions facilitated by the bromo-substituent. This reactivity is crucial for constructing complex molecular architectures.
- Incorporate it into the preparation of persistent room-temperature phosphorescent dyes. These materials offer unique optical properties for various applications.
- Employ this organic chemistry synthesis intermediate in the creation of advanced materials. Its structure is ideal for precursors in OLED and photoelectric material development.
Key Advantages
Versatile Synthesis Intermediate
As a key chemical intermediate, 3-bromo-2-fluorobenzonitrile is instrumental in the synthesis of a wide array of complex molecules, from pharmaceuticals to advanced materials.
Facilitates Advanced Reactions
The presence of both bromine and fluorine atoms allows for diverse chemical transformations, including palladium-catalyzed cross-coupling reactions, essential for modern organic synthesis.
Enables Novel Material Development
Its unique structure makes it a valuable precursor for developing high-performance materials, such as persistent room-temperature phosphorescent dyes and OLED materials.
Key Applications
Pharmaceutical Intermediates
As a fluorinated benzonitrile building block for drug discovery, it serves as a crucial starting material for synthesizing active pharmaceutical ingredients (APIs).
OLED and Photoelectric Materials
This compound is integral to the synthesis of OLED materials, contributing to advancements in display and lighting technologies.
Specialty Dyes
Its application extends to the creation of specialized dyes, including persistent room-temperature phosphorescent dyes, for various industrial and scientific uses.
Organic Chemistry Research
As a highly functionalized molecule, it is a key reagent in organic chemistry research, enabling exploration of new reaction pathways and molecular structures.