High-Purity (4-(N,N-Dimethylamino)phenyl)di-tert-butyl Phosphine Supplier: Enhance Catalysis Efficiency
(4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine is a premier choice for advanced chemical synthesis, widely utilized as a pharmaceutical intermediate and a powerful ligand in transition metal catalysis. Explore its benefits for your R&D and production needs.
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(4-(N,N-Dimethylamino)phenyl)di-tert-butyl Phosphine
As a dedicated manufacturer and supplier in China, we provide high-purity (4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine, essential for driving complex chemical transformations. This electron-rich and sterically demanding phosphine ligand is key to achieving higher yields and selectivity in crucial cross-coupling reactions for pharmaceutical intermediates and advanced materials.
- High electron donating capacity for enhanced oxidative addition in catalysis
- Steric bulk from tert-butyl groups promotes selectivity and reduces side reactions
- A reliable pharmaceutical intermediate for drug discovery and API manufacturing
- Source high-quality (4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine from a trusted China supplier
Key Advantages of Our Phosphine Ligands
Exceptional Electron-Richness
The synergistic effect of the N,N-dimethylamino group and tert-butyl substituents imbues this phosphine with superior electron-donating properties, significantly boosting the efficiency of the oxidative addition step in catalytic cycles. Discover how this can benefit your synthesis of pharmaceutical intermediates.
Enhanced Steric Control for Precision Synthesis
The substantial steric hindrance provided by the tert-butyl groups plays a critical role in preventing undesired side reactions and favoring the formation of monoligated metal complexes. This leads to improved regio- and chemoselectivity, making it an ideal choice for complex organic synthesis when you buy in bulk.
Stability for Practical Handling
Compared to some highly reactive phosphines, (4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine offers remarkable air and thermal stability under standard conditions. This makes it easier and safer to handle in both laboratory research and industrial production settings, ensuring supply chain reliability.
Diverse Applications in Modern Chemistry
Transition Metal Catalysis
As a premier ligand, it drives efficiency in crucial cross-coupling reactions like Suzuki–Miyaura, Heck, and Buchwald–Hartwig aminations, vital for forming complex molecular architectures in pharmaceutical intermediate synthesis.
Pharmaceutical Intermediate Synthesis
Its capability to facilitate efficient C–X bond formation makes it indispensable in drug discovery pipelines and the manufacturing of Active Pharmaceutical Ingredients (APIs). Purchase this key intermediate from our extensive catalog.
Material Science & Organic Electronics
In the synthesis of advanced materials, including OLED components, this ligand is instrumental in achieving high regioselectivity and improved yields during C–C coupling processes for conjugated systems.
Fine Chemical Manufacturing
Leverage the unique properties of this phosphine to optimize various organic synthesis routes, ensuring high purity and performance for a broad range of fine chemical products. Inquire about our bulk pricing for manufacturers.