DTSSP: Water-Soluble, Cleavable Amine-Amine Crosslinker for Precise Protein Modification
Discover the power of precise protein modification with DTSSP, a premium water-soluble and cleavable crosslinker. Ideal for researchers seeking reliable amine-to-amine conjugation, our high-purity product ensures optimal results in your life science applications. Inquire about bulk pricing and availability from our trusted manufacturing facility.
Get a Quote & SampleEnhance Your Bioconjugation with DTSSP: A Superior Crosslinking Solution

3,3'-Dithiobis(sulfosuccinimidylpropionate)
As a premier manufacturer and supplier of specialty biochemicals, we offer DTSSP, a high-purity, water-soluble, and cleavable homobifunctional crosslinker. Its unique properties, including amine reactivity and membrane impermeability, make it an essential tool for researchers. Trust us as your reliable supplier in China for consistent quality and competitive pricing.
- Amine-Reactive Sulfo-NHS Ester Groups: Facilitates selective conjugation with primary amines, crucial for accurate protein modification and mapping.
- Cleavable Disulfide Bond: Allows for reversible crosslinking, enabling further analysis or recovery of modified proteins using reducing agents.
- Water Solubility: Ensures ease of use in aqueous buffer systems, minimizing the need for organic solvents that can denature proteins.
- Membrane Impermeability: Ideal for cell surface labeling and crosslinking studies without affecting intracellular components, a key advantage for understanding cell surface interactions.
Key Advantages of DTSSP for Your Research
Precise Amine Conjugation
Leverage the sulfo-NHS ester reactivity of DTSSP for highly specific targeting of lysine residues and N-termini, essential for controlled protein structure analysis and drug delivery systems.
Controlled Cleavage and Analysis
Utilize the cleavable disulfide bond for applications requiring reversibility, such as protein-protein interaction studies or creating cleavable antibody-drug conjugates, ensuring flexibility in experimental design.
Enhanced Biocompatibility
Its excellent water solubility and membrane impermeability make DTSSP a safe and effective choice for in-situ protein crosslinking and studies on cell surface receptors, providing reliable data for researchers.
Diverse Applications of DTSSP in Life Sciences
Protein Structure Elucidation
Investigate protein-protein interactions and map protein complexes by employing DTSSP as a crosslinking reagent to stabilize transient or weak interactions, aiding in the understanding of biological pathways.
Bioconjugation and Drug Delivery
Form stable conjugates between proteins, peptides, and other biomolecules for targeted drug delivery systems or diagnostic assays. Purchase DTSSP to create custom bioconjugates.
Cell Surface Protein Modification
Study cell surface receptor-ligand interactions or immobilize cell surface proteins for analysis without intracellular perturbation, a critical application for membrane protein research.
Immobilization and Surface Chemistry
Utilize DTSSP for immobilizing proteins or other biomolecules onto surfaces like gold beads or microplates, enabling the development of biosensors and diagnostic platforms.