Rink Amide MBHA Resin: A Premier Solid Support for Fmoc-Based Peptide Synthesis

Discover the advantages of Rink Amide MBHA Resin for your Fmoc-based solid-phase peptide synthesis. As a leading manufacturer and supplier, we offer high-quality resins essential for efficient peptide amide production. Request your quote today!

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Key Advantages of Rink Amide MBHA Resin

Optimized for Fmoc Chemistry

Our Rink Amide MBHA Resin is fully compatible with the widely used Fmoc (9-fluorenylmethyloxycarbonyl) protection strategy, offering mild deprotection conditions that minimize side reactions and racemization, crucial for high-purity peptide synthesis.

Direct C-Terminal Amide Synthesis

This resin directly enables the synthesis of peptides with a C-terminal amide group (–CONH2), a common and vital feature in many natural peptides, hormones, and drug candidates. This simplifies the synthesis workflow by eliminating the need for post-synthesis amidation steps.

Versatile Cleavage and Deprotection

The MBHA linker in this resin is acid-labile, allowing for the cleavage of the peptide from the resin and the simultaneous removal of most acid-labile side-chain protecting groups using reagents like 95% TFA. This integrated deprotection and cleavage step streamlines the purification process.

Applications of Rink Amide MBHA Resin

Peptide Synthesis

The primary application of Rink Amide MBHA Resin is in solid-phase peptide synthesis (SPPS), enabling the construction of complex peptide sequences for various research purposes.

Drug Discovery & Development

Researchers utilize this resin to synthesize peptide-based drug candidates and libraries, accelerating the drug discovery process for therapeutic applications.

Bioconjugation

It serves as a reliable platform for creating peptide conjugates, which are essential for targeted drug delivery systems, diagnostics, and vaccine development.

Academic and Industrial Research

From university labs to pharmaceutical manufacturers, this resin is a standard tool for both basic research and industrial-scale peptide production.