Selective Radical-Type Perfluoro-tert-butylation with a Stable Reagent
Introducing a breakthrough in fluorine chemistry: a stable and scalable reagent for efficient perfluoro-tert-butylation, enabling precise control over E/Z selectivity in unsaturated compounds through innovative photocatalysis.
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Perfluoro-tert-butanol
Perfluoro-tert-butanol serves as a pivotal building block for advanced fluorine-containing molecules, with significant applications in magnetic resonance imaging, material science, and drug design. As a leading supplier in China, we provide high-quality perfluoro-tert-butanol, ensuring purity and reliability for your demanding synthesis needs.
- Discover the latest advancements in the synthesis of PFtB-containing compounds using perfluoro-tert-butylation of alkenes, a key area for novel material development.
- Explore efficient photocatalytic C-H functionalization strategies that leverage perfluoro-tert-butanol for precise molecular modification.
- Understand the mechanisms behind selective perfluoro-tert-butylation of styrenes, offering unparalleled control over stereochemistry.
- Learn how hypervalent iodine reagents derived from perfluoro-tert-butanol are transforming radical chemistry for broader synthetic applications.
Key Advantages
Enhanced Selectivity
Achieve remarkable E/Z selectivity in perfluoro-tert-butylation of styrenes through a controllable triplet-triplet energy transfer (TTET) process, a significant leap from traditional methods.
Scalable and Stable Reagent
Utilize a synthesized hypervalent iodine(III) reagent derived from perfluoro-tert-butanol that is both stable and scalable, facilitating its use in large-scale chemical production.
Versatile Synthetic Platform
Leverage a broad synthetic platform for the perfluoro-tert-butylation of unsaturated compounds, including alkenes, alkynes, and electron-rich aromatics, expanding the scope of fluorine chemistry.
Key Applications
Pharmaceutical Intermediates
Explore the use of perfluoro-tert-butanol in the synthesis of complex pharmaceutical intermediates, leveraging its unique chemical properties for drug discovery.
Magnetic Resonance Imaging (MRI)
Discover the role of PFtB-containing compounds in high-performance fluorine-19 MRI agents, enhancing diagnostic capabilities through superior imaging properties.
Material Science
Investigate the incorporation of the perfluoro-tert-butyl group into advanced materials, tailoring properties for specific technological applications.
Agrochemicals
Utilize perfluoro-tert-butylation strategies to develop novel agrochemicals with improved efficacy and stability.