Sulfo-SMCC: Your Partner in Advanced Bioconjugation
Discover the power of Sulfo-SMCC, a premier water-soluble heterobifunctional crosslinker designed for precise protein modification and bioconjugation. Unlock new possibilities in drug delivery and diagnostics.
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Sulfo-SMCC Sodium Salt
Sulfo-SMCC is a highly effective water-soluble heterobifunctional crosslinker, widely utilized by researchers and manufacturers. As a reliable supplier in China, we provide high-purity Sulfo-SMCC that enables specific conjugation between molecules containing amine and sulfhydryl groups. Its unique structure, featuring a sulfo-NHS ester and a maleimide functional group, facilitates efficient bioconjugation reactions without the need for organic solvents, ensuring protein integrity.
- Amine to Sulfhydryl Crosslinking: Sulfo-SMCC facilitates the precise linkage of molecules with primary amines and sulfhydryl groups, a crucial step in many bioconjugation strategies.
- Enhanced Water Solubility: The presence of sulfo moieties grants excellent water solubility, allowing for reactions in physiological buffer conditions, a key advantage for protein modification.
- Stable Maleimide Group: The cyclohexane spacer arm enhances the stability of the maleimide group, ensuring efficient and reliable reactions in various protein labeling applications.
- Versatile Applications: This reagent is instrumental in creating antibody-enzyme conjugates, antibody-drug conjugates (ADCs), and other sophisticated bioconjugates for research and development.
Key Advantages Offered
Precise Conjugation Control
Leverage Sulfo-SMCC for controlled conjugation, ensuring targeted attachment of molecules. This precision is vital when preparing maleimide activated bioconjugates for specific biological applications.
Biomolecule Integrity Preservation
Its water solubility allows reactions in aqueous buffers, preserving the structural integrity and activity of sensitive biomolecules, unlike crosslinkers requiring organic solvents for protein conjugation.
Streamlined Workflow
Sulfo-SMCC simplifies complex bioconjugation processes, making it easier to achieve desired outcomes in antibody enzyme conjugation and related fields.
Key Applications
Antibody-Drug Conjugates (ADCs)
Utilize Sulfo-SMCC in the development of ADCs, a crucial area for targeted cancer therapies, enabling precise linking of antibodies to cytotoxic drugs.
Protein Labeling
Ideal for labeling proteins with enzymes, fluorophores, or other tags for use in diagnostics and research, supporting various protein labeling technologies.
Surface Modification
Modify surfaces with biomolecules for improved biocompatibility or specific binding properties, crucial in biosensor development and biomaterial engineering.
General Bioconjugation
A fundamental tool for creating diverse bioconjugates, supporting numerous research endeavors in chemistry and biology, and acting as a key pharmaceutical intermediate.