1-Hydroxy-7-azabenzotriazole (HOAt): The Key to Efficient Peptide Synthesis

Discover the power of 1-Hydroxy-7-azabenzotriazole (HOAt), a premier coupling reagent from NINGBO INNO PHARMCHEM CO.,LTD. that significantly enhances peptide synthesis efficiency and purity, minimizing unwanted side reactions for critical research and manufacturing.

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Why Choose HOAt for Your Peptide Synthesis Needs?

Exceptional Coupling Performance

HOAt is renowned for its ability to facilitate amide bond formation with remarkable efficiency, especially when used in conjunction with carbodiimide reagents. Its structure promotes faster reaction kinetics, leading to higher yields of your target peptides.

Suppresses Racemization

A critical advantage of using HOAt in peptide synthesis is its proven efficacy in suppressing epimerization and racemization, particularly with sterically hindered amino acids. This ensures the chiral purity of your final peptide product, a vital factor in pharmaceutical applications.

Versatile Applications

Beyond its primary role as a coupling reagent, HOAt is a foundational component for other highly effective peptide condensation agents like HATU. This versatility makes it an essential tool for researchers exploring novel peptide sequences and complex molecular structures.

Key Application Areas for HOAt

Peptide Synthesis

The primary application of HOAt is as a high-efficiency coupling reagent in solid-phase and solution-phase peptide synthesis, enabling the formation of peptide bonds with reduced side reactions.

Pharmaceutical Intermediates

As a critical intermediate, HOAt is vital for the synthesis of various pharmaceutical compounds, including peptide-based drugs and complex biomolecules. Buy HOAt to advance your drug discovery pipelines.

Biomolecular Research

Researchers in biomolecular science utilize HOAt to construct complex peptides for studying protein function, developing diagnostics, and creating therapeutic agents. Purchase HOAt for cutting-edge research.

Chemical Synthesis

HOAt finds application in various organic synthesis pathways where efficient amide bond formation is required, contributing to the development of novel chemical entities. Contact us for a quote on our HOAt supply.