2-(Carbobenzoxyamino)-1-ethanol

Product Overview

2-(Carbobenzoxyamino)-1-ethanol, commonly known in the industry as Z-Glycinol or Z-Gly-ol, represents a critical protected amino alcohol utilized extensively in organic synthesis and peptide chemistry. This compound features a carbobenzoxy (Cbz) protecting group attached to the nitrogen atom of ethanolamine, providing stability during various chemical transformations. As a key building block, it facilitates the construction of complex peptide sequences and heterocyclic structures while preventing unwanted side reactions at the amine functionality.

Our manufacturing process ensures that every batch meets rigorous international standards for pharmaceutical intermediates. The compound is characterized by its high chemical stability and excellent solubility profile in common organic solvents, making it a versatile reagent for laboratory and industrial-scale synthesis. We prioritize consistency and reliability, ensuring that our clients receive material that performs predictably in downstream applications.

Technical Specifications

Industrial Applications

This protected amino alcohol serves as a fundamental precursor in the synthesis of biologically active molecules. Its primary utility lies in the field of peptide synthesis, where the Cbz group offers orthogonal protection strategies compatible with various coupling conditions. Beyond peptides, it is employed in the preparation of pharmaceutical intermediates requiring a protected hydroxyethylamine motif.

• Peptide Chain Elongation: Acts as a stable nucleophile in coupling reactions.
• Heterocyclic Synthesis: Used to construct oxazolidinones and related ring systems.
• Pharmaceutical Intermediates: Key starting material for drug substance manufacturing.
• Chemical Research: Standard reagent for method development in organic chemistry.

Quality Assurance and Storage

Quality control is paramount in our production facility. Each lot undergoes comprehensive analysis using High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to guarantee compliance with specified parameters.

To maintain optimal stability, the product should be stored in a cool, dry environment at temperatures between 0-5 °C. Containers must remain tightly closed to prevent moisture absorption, which could affect physical properties over time. Proper handling ensures the material retains its reactivity and purity throughout its shelf life. We offer flexible packaging options, including 25 kg drums, to accommodate diverse logistical requirements for global distribution.