2'-Deoxyguanosine 5'-monophosphate

Product Overview

2'-Deoxyguanosine 5'-monophosphate, commonly abbreviated as dGMP, represents a fundamental nucleotide building block essential for various biochemical applications. As a phosphorylated derivative of deoxyguanosine, this compound plays a critical role in DNA synthesis and enzymatic studies. Our facility specializes in the production of high-purity dGMP, ensuring consistency for research laboratories and pharmaceutical manufacturing processes. The chemical structure features a guanine base linked to a deoxyribose sugar and a phosphate group at the 5' position, making it a key substrate for kinases and polymerases. The molecular weight of approximately 347.22 g/mol facilitates precise molar calculations for experimental designs.

Technical Specifications

Industrial Applications

This nucleotide is extensively utilized in molecular biology research, particularly in the synthesis of oligonucleotides and DNA sequencing protocols. It serves as a vital substrate for guanylate kinase, facilitating studies on nucleotide metabolism and energy transfer within cellular systems. In the pharmaceutical sector, dGMP acts as a critical intermediate for the development of antiviral agents and anticancer therapeutics targeting nucleic acid pathways. Researchers rely on its stability and reactivity for enzymatic assays and cell culture supplementation. Furthermore, its compatibility with various buffer systems makes it suitable for in vitro transcription and translation experiments. The compound's solubility in aqueous solutions allows for easy preparation of stock solutions for immediate use in laboratory settings.

Quality Assurance and Handling

We adhere to strict quality control measures to guarantee the integrity of every batch. Each production lot undergoes rigorous testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. This ensures that the assay purity meets or exceeds the specified threshold of 98.0 percent. Impurities are monitored closely to prevent interference in sensitive biochemical reactions. Our manufacturing process is designed to minimize degradation, preserving the chemical stability of the phosphate ester bond. Temperature control during transport is recommended to prevent thermal degradation. Our team provides technical support to assist with integration into your specific workflow.

Storage and Packaging

To maintain optimal quality, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper sealing is crucial to prevent hydrolysis of the phosphate group. We offer flexible packaging solutions, including standard 25 kg drums, with customization available to meet specific logistical requirements. Global shipping capabilities ensure timely delivery to research institutions and industrial clients worldwide. Documentation such as Certificates of Analysis (COA) and Safety Data Sheets (SDS) are provided with every shipment.