Ac-Asp(OtBu)-OH
- CAS No.117833-18-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Ac-Asp(OtBu)-OH is a high-purity protected amino acid derivative essential for peptide synthesis. We supply pharmaceutical grade material with full documentation.
Request a Quote & Full COAProduct Technical Details
Product Overview
Ac-Asp(OtBu)-OH, chemically known as N-Acetyl-L-aspartic acid 4-tert-butyl ester, represents a critical building block in the realm of advanced pharmaceutical synthesis. As a protected amino acid derivative, this compound plays a pivotal role in the construction of complex peptide chains and active pharmaceutical ingredients (APIs). Our manufacturing facility is dedicated to producing this specialty chemical with uncompromising quality standards, ensuring consistency for research and industrial applications alike.
The presence of the tert-butyl ester protecting group on the side chain carboxyl function allows for selective reactivity during peptide coupling processes. This specificity is vital for preventing unwanted side reactions, thereby enhancing the overall yield and purity of the final peptide product. We understand the stringent requirements of modern drug discovery and provide material that meets these rigorous demands.
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Name | Ac-Asp(OtBu)-OH |
| CAS Number | 117833-18-8 |
| Molecular Formula | C10H17NO5 |
| Molecular Weight | 231.25 g/mol |
| Appearance | White Powder |
| Purity | ≥98.0% (HPLC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 449.6±40.0 °C at 760 mmHg |
| Flash Point | 225.7±27.3 °C |
Industrial Applications
This protected amino acid is primarily utilized as a key intermediate in the synthesis of therapeutic peptides. Its stability under various reaction conditions makes it suitable for both solid-phase peptide synthesis (SPPS) and solution-phase methodologies. Researchers and process chemists rely on Ac-Asp(OtBu)-OH for the development of neurological therapeutics and other complex biological modulators where precise amino acid sequencing is required.
- High compatibility with standard coupling reagents.
- Excellent stability during storage and handling.
- Minimal racemization risk during activation.
- Ideal for scale-up from laboratory to commercial production.
Quality Assurance and Packaging
Quality control is the cornerstone of our operation. Every batch of Ac-Asp(OtBu)-OH undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with international standards.
Standard packaging consists of 25 kg drums, designed to maintain product integrity during transit. However, we offer flexible packaging solutions tailored to specific customer requirements. To preserve the chemical stability of the material, storage at 2-8ºC is recommended. Containers should remain tightly closed in a cool, dry environment away from direct sunlight and moisture. Our global logistics network ensures timely delivery to support your production schedules without interruption.
