Peptides & Building Blocks

Boc-4-Nitro-L-Phenylalanine

  • CAS No.33305-77-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Boc-4-Nitro-L-Phenylalanine for peptide synthesis. Reliable supply with COA and global shipping options available for bulk orders.

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Product Technical Details

Product Overview

Boc-4-Nitro-L-Phenylalanine is a highly specialized protected amino acid derivative designed for advanced peptide synthesis and pharmaceutical research. As a critical building block, this compound features a tert-butoxycarbonyl (Boc) protecting group on the alpha-amino function and a nitro group at the para-position of the phenyl ring. This unique structural configuration provides exceptional stability during synthetic processes while offering versatile reactivity for downstream modifications. Our manufacturing process ensures high optical purity and chemical integrity, making it an ideal choice for complex molecule assembly in both academic and industrial settings.

The presence of the nitro group allows for further chemical transformations, such as reduction to the corresponding aniline derivative, which is valuable in the development of novel therapeutic agents. We prioritize consistent quality across all batches, ensuring that researchers and production teams can rely on our materials for reproducible results in sensitive synthetic pathways.

Technical Specifications

ParameterValue
CAS Number33305-77-0
Molecular FormulaC14H18N2O6
Molecular Weight310.30 g/mol
AppearanceWhite Powder
Purity≥99.0%
Melting Point107°C
Density1.29 g/cm3

All specifications are verified through rigorous analytical testing including HPLC and NMR spectroscopy. We maintain strict control over impurities to meet the demanding standards of modern pharmaceutical development.

Applications and Usage

This protected amino acid is primarily utilized in solid-phase peptide synthesis (SPPS) and solution-phase synthesis. It serves as a key intermediate in the construction of bioactive peptides and peptidomimetics. The Boc protection strategy is particularly useful in orthogonal protection schemes where acid-labile groups are required. Additionally, the nitro functionality provides a handle for subsequent chemical diversification, enabling the creation of specialized libraries for drug discovery programs.

  • Ideal for pharmaceutical intermediate synthesis
  • Compatible with standard Boc deprotection conditions
  • Suitable for custom peptide manufacturing
  • Used in the development of neurological therapeutics

Quality Assurance and Storage

Quality is paramount in our production facility. Each batch of Boc-4-Nitro-L-Phenylalanine is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against established specifications. We adhere to Good Manufacturing Practices (GMP) guidelines to ensure product safety and consistency. For storage, the material should be kept in a tightly closed container in a cool, dry place, ideally at temperatures below -20°C for long-term stability. Proper handling ensures the preservation of optical purity and prevents degradation due to moisture or heat exposure.

We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom requirements based on project needs. Our global logistics network ensures timely delivery to support your research and production schedules without interruption.