Peptides & Building Blocks

Boc-O-Methyl-D-serine

  • CAS No.86123-95-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Boc-O-Methyl-D-Serine (CAS 86123-95-7) designed for pharmaceutical intermediate synthesis and peptide coupling applications.

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Product Technical Details

Product Overview

Boc-O-Methyl-D-serine is a highly specialized protected amino acid derivative that serves as a critical building block in modern organic synthesis and pharmaceutical manufacturing. This chiral compound features a tert-butyloxycarbonyl (Boc) protecting group on the amine functionality and a methyl ether modification on the side chain hydroxyl group. These structural features provide exceptional stability during complex multi-step synthesis routes, preventing unwanted side reactions while maintaining stereochemical integrity. Our facility produces this material under strict quality control standards to ensure consistency for research and industrial scale applications.

Technical Specifications

ParameterValue
Chemical NameBoc-O-Methyl-D-serine
CAS Number86123-95-7
Molecular FormulaC9H17NO5
Molecular Weight219.235 g/mol
AppearanceColorless to light yellow oily liquid
Assay (Purity)≥98.0%
Density1.1±0.1 g/cm3
Boiling Point355.8±37.0 °C at 760 mmHg
Flash Point169.0±26.5 °C
Refractive Index1.461

Industrial Applications

This protected amino acid is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Notably, it serves as a crucial precursor in the manufacturing process of Lacosamide, an antiepileptic medication. The high optical purity of our D-serine derivative ensures that the final pharmaceutical product meets stringent regulatory requirements for chirality. Beyond specific API synthesis, this compound is widely employed in peptide chemistry where orthogonal protection strategies are required. The Boc group allows for selective deprotection under acidic conditions, while the O-methyl group remains stable, offering chemists precise control over reaction sequences.

Quality Assurance and Storage

We understand that reliability is paramount in pharmaceutical supply chains. Each batch of Boc-O-Methyl-D-serine undergoes rigorous analytical testing including HPLC, NMR, and specific rotation analysis to verify identity and purity. We provide a comprehensive Certificate of Analysis (COA) with every shipment to document compliance with specifications. For optimal preservation of chemical stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. We offer flexible packaging solutions including 200 kg drums or custom configurations based on client logistical requirements. Our global distribution network ensures timely delivery while maintaining cold chain integrity where necessary.

  • High stereochemical purity for sensitive synthesis
  • Stable protecting groups for multi-step reactions
  • Verified intermediate for pharmaceutical manufacturing
  • Comprehensive quality documentation provided
  • Scalable supply for industrial production needs