(S)-N-Boc-2-Amino-3-Methoxy-Propionic Acid

Product Overview

(S)-N-Boc-2-Amino-3-Methoxy-Propionic Acid, frequently recognized in the industry as Boc-O-Methyl-L-Serine or Boc-Ser(Me)-OH, stands as a critical protected amino acid derivative utilized extensively in the field of organic synthesis and peptide chemistry. This specialized building block features a tert-butoxycarbonyl (Boc) protecting group on the alpha-amino function and a methyl ether modification on the side chain hydroxyl group. Such structural configuration provides exceptional stability against racemization during coupling reactions, making it an indispensable reagent for the construction of complex peptide sequences and modified protein structures.

Our manufacturing process adheres to stringent quality control protocols to ensure consistent chemical integrity. The product is synthesized using advanced catalytic methods that maximize yield while minimizing impurities. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurements, to guarantee compliance with international pharmaceutical standards. The high optical purity ensures that downstream peptide products maintain their desired biological activity and stereochemical configuration.

Key Specifications

Industrial Applications

This protected amino acid serves as a fundamental precursor in the development of therapeutic peptides, diagnostic agents, and biochemical research tools. The O-methyl modification alters the hydrophilicity and metabolic stability of the resulting peptide, offering researchers greater flexibility in drug design. It is particularly valuable in solid-phase peptide synthesis (SPPS) where orthogonal protection strategies are required.

• Pharmaceutical Intermediate for Peptide Drug Development
• Building Block for Modified Protein Synthesis
• Reagent for Biochemical Research and Structure-Activity Studies
• Component in Custom Peptide Library Construction
• Standard for Analytical Method Validation in QC Labs

Quality Assurance and Supply

As a global manufacturer, we prioritize supply chain reliability and product safety. Our facility operates under Good Manufacturing Practice (GMP) guidelines, ensuring that every drum meets the specified quality criteria. We provide comprehensive documentation with each shipment, including Certificates of Analysis (COA), Method Validation Reports, and Stability Data. Our logistics network supports temperature-controlled shipping to maintain product integrity during transit. For large-scale projects, we offer flexible packaging solutions ranging from laboratory scales to multi-ton industrial quantities, ensuring seamless integration into your production workflow.

Storage and Handling

To maintain optimal quality, store this material in a tightly closed container at -15°C or in a cool, dry place away from direct sunlight and moisture. Avoid exposure to strong oxidizing agents. When handling, use appropriate personal protective equipment including gloves and safety goggles to prevent skin or eye contact. Proper ventilation is recommended during weighing and dispensing operations to minimize inhalation of dust particles. Following these guidelines ensures the longevity and performance of the chemical in your synthesis processes.