D-alpha-Cyclohexylglycine
- CAS No.14328-52-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity D-alpha-Cyclohexylglycine (CAS 14328-52-0) designed for pharmaceutical peptide synthesis. Reliable chiral building block with strict quality control.
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Product Overview
D-alpha-Cyclohexylglycine is a specialized non-proteinogenic amino acid derivative that serves as a critical chiral building block in modern medicinal chemistry. Characterized by its unique cyclohexyl side chain, this compound introduces significant conformational constraints and enhanced lipophilicity into peptide structures. These properties are essential for optimizing the pharmacokinetic profiles of therapeutic peptides, including improved metabolic stability and receptor binding affinity. Our manufacturing process ensures consistent stereochemical integrity, making it an ideal choice for complex drug discovery programs.
As a key intermediate in the synthesis of bioactive peptides, this material supports the development of next-generation pharmaceuticals. The D-configuration provides specific spatial orientation required for interacting with chiral biological targets. Researchers and procurement managers rely on this compound for its reliability in solid-phase peptide synthesis and solution-phase coupling reactions. We maintain rigorous production standards to meet the demanding specifications of the global pharmaceutical industry.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 14328-52-0 |
| Molecular Formula | C8H15NO2 |
| Molecular Weight | 157.210 |
| Appearance | White to off-white powder |
| Assay | ≥99.0% |
| Specific Rotation | -30°~ -32°(C=1, 1N HCl) |
| Loss on Drying | ≤0.50% |
| Isomer Purity | ≤1.0% |
Industrial Applications
This amino acid derivative is primarily utilized in the preparation of peptide-based therapeutics and enzyme inhibitors. The cyclohexyl group acts as a robust hydrophobic moiety that can significantly alter the solubility and membrane permeability of the final drug candidate. It is frequently employed in the design of protease inhibitors and hormonal analogs where structural rigidity is paramount. Furthermore, its high chemical stability allows it to withstand various synthesis conditions without racemization, ensuring the final product maintains its intended biological activity.
Beyond direct pharmaceutical use, this compound supports research in chemical biology and structure-activity relationship studies. Laboratories require high-purity materials to validate synthetic routes and ensure reproducible results. Our supply chain is optimized to deliver bulk quantities consistently, supporting both pilot-scale experiments and commercial manufacturing campaigns. We understand the critical nature of timeline adherence in drug development and prioritize efficient logistics.
Quality Assurance and Safety
Quality is the cornerstone of our manufacturing philosophy. Every batch of D-alpha-Cyclohexylglycine undergoes comprehensive analytical testing using advanced techniques such as HPLC, NMR, and polarimetry. We provide a detailed Certificate of Analysis with every shipment to verify compliance with specified parameters. Our facilities adhere to strict safety and environmental protocols, ensuring that all products are handled and stored under controlled conditions to prevent degradation.
- Strict control of chiral purity to minimize isomer contamination.
- Comprehensive traceability from raw materials to finished goods.
- Stable packaging designed to protect against moisture and light.
- Technical support available for synthesis optimization and troubleshooting.
- Global compliance with chemical safety regulations and shipping standards.
Storage and Packaging
To maintain optimal quality, this product should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed when not in use to prevent exposure to atmospheric moisture. We offer flexible packaging options, including standard 25kg drums, with custom configurations available upon request. Our logistics team ensures secure handling during transit to guarantee that the material arrives in perfect condition for immediate use in your production processes.
