D-Arginine
- CAS No.157-06-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity D-Arginine (CAS 157-06-2) designed for advanced peptide synthesis and biochemical research applications with strict chiral specifications.
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Product Overview
D-Arginine is a crucial chiral amino acid building block extensively utilized in the field of advanced organic synthesis and peptide engineering. As the D-enantiomer of the naturally occurring L-Arginine, this compound plays a pivotal role in modifying the structural stability and metabolic resistance of synthetic peptides. Our manufacturing process ensures exceptional optical purity, making it an ideal candidate for research laboratories and pharmaceutical development teams focusing on novel therapeutic structures.
The production of D-Arginine requires precise stereochemical control to minimize the presence of the L-isomer, which could interfere with specific biological assays or synthetic pathways. We employ rigorous crystallization and purification techniques to achieve assay levels exceeding 98.5 percent, ensuring consistency across batches for large scale production needs.
Key Specifications and Quality Parameters
Quality control is paramount in the supply of fine chemical intermediates. The following table outlines the critical physical and chemical parameters verified for every batch of D-Arginine supplied from our facility. These specifications guarantee the material meets the demanding requirements of modern peptide synthesis.
| Parameter | Specification |
|---|---|
| Solubility in water | Colorless and clear (c=5) |
| Specific rotation [α]D20 | -26.5° to -27.8° (c= 8, 6M-HCl) |
| Loss on drying | Not more than 0.5% |
| Residue on ignition (as sulfate) | Not more than 0.2% |
| Chloride (Cl) | Not more than 0.05% |
| Sulfate (SO4) | Not more than 0.03% |
| Heavy metals (as Pb) | Not more than 10ppm |
| Iron (Fe) | Not more than 10ppm |
| Ammonium (NH4) | Not more than 0.02% |
| Arsenic (As2O3) | Not more than 1ppm |
| Other amino acids | Not detected by T.L.C. (20μg) |
| Assay | 98.5% to 101.0% |
| L-Isomer | Not more than 0.5% |
Industrial Applications
Primarily, D-Arginine serves as a fundamental building block in the synthesis of bioactive peptides where enzymatic stability is required. Incorporating D-amino acids into peptide sequences can significantly enhance resistance to proteolytic degradation, thereby extending the half life of potential drug candidates. Additionally, this compound is utilized in biochemical research to study receptor binding affinities and stereoselective interactions within complex biological systems.
Quality Assurance and Packaging
Every shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing the test results against the specifications listed above. Our quality assurance team conducts multiple checkpoints during the manufacturing process to ensure that impurities such as heavy metals, residual solvents, and cross contamination with L-isomers are kept to absolute minimum levels. We offer flexible packaging options to suit both laboratory scale research and industrial scale production requirements, ensuring safe and compliant global delivery.
