Peptides & Building Blocks

D-Norleucine

  • CAS No.327-56-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity D-Norleucine (CAS 327-56-0) designed for advanced peptide synthesis and pharmaceutical research applications.

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Product Technical Details

Product Overview

D-Norleucine represents a critical chiral building block within the realm of advanced pharmaceutical research and peptide engineering. As a non-proteinogenic amino acid, this compound offers unique structural properties that are essential for modifying peptide stability and biological activity. Our facility specializes in the production of high-purity D-Norleucine, catering to the rigorous demands of laboratory synthesis and industrial applications. The compound is characterized by its specific stereochemistry, which distinguishes it from its L-isomer counterpart, providing researchers with the necessary tools for precise molecular design and development.

Industrial Applications

In the context of peptide synthesis, D-Norleucine serves as a valuable intermediate for creating analogs with enhanced metabolic stability. By incorporating this residue into peptide chains, scientists can investigate structure-activity relationships and develop novel therapeutic candidates. The versatility of this amino acid extends to conformational studies, where it helps in understanding the spatial arrangement of complex biomolecules. Furthermore, it acts as a key component in the development of specialized reagents used across various biochemical assays. Our commitment to quality ensures that each batch meets the stringent requirements necessary for sensitive research environments and large-scale production needs.

Quality Specifications

The manufacturing process employs advanced purification techniques to minimize impurities and ensure consistent optical rotation. We maintain strict control over potential contaminants such as heavy metals, residual solvents, and related amino acids. This dedication to purity is reflected in our comprehensive quality assurance protocols, which include detailed testing for loss on drying, residue on ignition, and specific rotation. The resulting product offers reliable performance in synthetic routes, reducing the risk of side reactions or failed experiments. Clients can depend on our supply chain for timely delivery and consistent specifications across large-scale orders.

ParameterSpecification
Solubility in 3M-HClColorless and clear (c=4)
Specific Rotation [alpha]D20-23.5 to -24.5 degrees (c=4, 6M-HCl)
Loss on DryingNot more than 0.3 percent
Residue on IgnitionNot more than 0.1 percent
Assay98.5 percent to 101.0 percent
L-Isomer ImpurityNot more than 0.5 percent
Heavy Metals (as Pb)Not more than 10 ppm

Safety and Logistics

Safety and handling procedures align with standard laboratory practices for chemical intermediates. Proper storage conditions are recommended to maintain stability over extended periods, typically in a cool and dry environment away from direct sunlight. Our technical support team is available to provide guidance on application-specific requirements and documentation needs. Whether for academic research or industrial development, our D-Norleucine provides a foundational element for innovation in chemical biology. We invite partners to collaborate with us for their sourcing needs, benefiting from our experience as a global manufacturer committed to excellence and regulatory compliance.