D-Norvaline
- CAS No.2013-12-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity D-Norvaline designed for advanced peptide synthesis and pharmaceutical intermediates with strict optical rotation control.
Request a Quote & Full COAProduct Technical Details
Product Overview
D-Norvaline, chemically known as (2R)-2-aminopentanoic acid, is a non-proteinogenic chiral amino acid that serves as a critical building block in modern organic synthesis. Our facility specializes in the production of high-optical-purity D-Norvaline, catering to the rigorous demands of the pharmaceutical and biotechnology sectors. This compound is essential for the construction of complex peptide structures and acts as a key intermediate in the manufacturing of various therapeutic agents.
As a leading manufacturer, we ensure that every batch undergoes stringent quality control measures to guarantee stereochemical integrity. The specific rotation values are tightly monitored to prevent racemization, ensuring that downstream synthesis processes yield consistent and reliable results. Our production capabilities allow for scalable supply without compromising on the purity profiles required for sensitive research and development applications.
Technical Specifications
We adhere to international quality standards to provide a product that meets the exacting needs of chemical synthesis. The following table outlines the key physical and chemical parameters verified during our quality assurance process.
| Parameter | Specification |
|---|---|
| Solubility in 3M-HCl | Colorless and clear solution (c=5) |
| Specific Rotation [α]D20 | -23.5° to -25.5° (c= 10, 6M-HCl) |
| Loss on Drying | Not more than 0.3% |
| Residue on Ignition | Not more than 0.1% (as sulfate) |
| Chloride (Cl) | Not more than 0.03% |
| Sulfate (SO4) | Not more than 0.03% |
| Heavy Metals (as Pb) | Not more than 10ppm |
| Iron (Fe) | Not more than 10ppm |
| Ammonium (NH4) | Not more than 0.02% |
| Arsenic (As2O3) | Not more than 1ppm |
| Other Amino Acids | Not detected by T.L.C. (20μg spotted) |
| Assay | 98.5% to 101.0% |
| L-Isomer Impurity | Not more than 0.5% |
Industrial Applications
The primary utility of D-Norvaline lies in its role as a versatile synthon for peptide chemistry. It is frequently employed in the solid-phase synthesis of modified peptides where non-natural amino acids are required to enhance stability or biological activity. Furthermore, this compound is utilized in the development of antihypertensive medications and other cardiovascular therapeutics where chiral precision is paramount.
Research laboratories also leverage D-Norvaline for structure-activity relationship studies. Its unique side chain structure allows chemists to probe steric and electronic effects within peptide backbones. Whether for large-scale manufacturing or small-batch research, our product provides the consistency needed for reproducible experimental outcomes.
Quality Assurance and Packaging
Quality is the cornerstone of our manufacturing philosophy. Each production lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing all test results against the specifications listed above. We utilize advanced analytical techniques, including high-performance liquid chromatography (HPLC) and polarimetry, to verify assay purity and optical rotation.
Our packaging solutions are designed to maintain product stability during transit and storage. Materials are selected to prevent moisture uptake and contamination, ensuring the chemical integrity remains intact upon arrival. We support global logistics networks to deliver bulk quantities efficiently to partners worldwide, facilitating seamless integration into your supply chain.
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