Peptides & Building Blocks

D-tert-Leucine

  • CAS No.26782-71-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

D-tert-Leucine is a high-purity non-natural amino acid essential for pharmaceutical peptide synthesis. We offer bulk quantities with strict quality control and reliable global shipping.

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Product Technical Details

Product Overview

D-tert-Leucine, also known by its systematic name (R)-2-Amino-3,3-dimethylbutyric acid, is a critical non-natural amino acid derivative widely utilized in the pharmaceutical and biotechnology sectors. As a chiral building block, it plays a pivotal role in the synthesis of complex peptide structures and protease inhibitors. Our facility specializes in the production of this high-value intermediate, ensuring consistent quality and supply chain stability for research and industrial applications.

The unique steric hindrance provided by the tert-butyl group in D-tert-Leucine makes it an indispensable component in designing peptides with enhanced metabolic stability and biological activity. This compound is particularly valued in the development of therapeutic agents where specific conformational constraints are required to optimize drug efficacy.

Technical Specifications

We adhere to rigorous manufacturing standards to guarantee the purity and reliability of every batch. The following table outlines the key physical and chemical properties of our premium grade D-tert-Leucine.

ParameterSpecification
CAS Number26782-71-8
Molecular FormulaC6H13NO2
Molecular Weight131.173 g/mol
AppearanceWhite to off-white powder
Assay (Purity)≥98.0%
Loss on Drying≤0.5%
Melting Point>300°C
Storage ConditionsCool, dry, well-ventilated place

Industrial Applications

This amino acid derivative serves as a fundamental intermediate in the synthesis of various pharmaceutical compounds. Its primary applications include:

  • Peptide Drug Synthesis: Used as a building block for constructing bioactive peptides with improved pharmacokinetic profiles.
  • Protease Inhibitors: Essential component in the development of inhibitors targeting viral and cellular proteases.
  • Organic Synthesis: Employed in asymmetric synthesis routes requiring chiral auxiliaries or specific steric bulk.
  • Research and Development: Widely used in academic and industrial laboratories for method development and structure-activity relationship studies.

Quality Assurance and Control

Quality is the cornerstone of our manufacturing process. Every batch of D-tert-Leucine undergoes comprehensive testing using advanced analytical techniques such as High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR). We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes to ensure compliance with your internal standards and regulatory requirements.

Packaging and Storage

To maintain product integrity during transit, D-tert-Leucine is packaged in secure 25kg drums. Custom packaging solutions are available upon request to meet specific logistical needs. The product should be stored in a cool, dry environment with the container tightly closed to prevent moisture absorption and contamination. Proper storage ensures the long-term stability and performance of the material.

Why Choose Our Supply

As a global manufacturer with over two decades of experience, we offer competitive bulk pricing without compromising on quality. Our dedicated technical support team is available to assist with synthesis route optimization and application guidance. We prioritize quick delivery and reliable communication to support your production schedules and research timelines.