D-Valine
- CAS No.640-68-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity D-Valine (CAS 640-68-6) serves as a critical chiral building block for pharmaceutical synthesis and peptide coupling, available in bulk quantities with comprehensive COA.
Request a Quote & Full COAProduct Technical Details
Product Overview
D-Valine, chemically known as (R)-2-Amino-3-methylbutanoic acid, is a crucial optically active amino acid utilized extensively in the fine chemical and pharmaceutical industries. As a fundamental chiral building block, it plays an indispensable role in the asymmetric synthesis of complex organic molecules. Our facility produces high-grade D-Valine under strict quality management systems, ensuring consistent optical purity and chemical stability suitable for demanding research and industrial applications.
This enantiomerically pure compound is distinct from its L-isomer counterpart and is specifically valued for its unique stereochemical properties. It serves as a key starting material for the construction of peptide chains, pharmaceutical intermediates, and specialized agrochemical compounds. The manufacturing process employs advanced resolution techniques to guarantee minimal L-isomer contamination, meeting the rigorous standards required for chiral drug development.
Key Specifications
We maintain tight control over physical and chemical parameters to ensure product reliability. The following table outlines the typical specifications for our bulk supply:
| Parameter | Specification |
|---|---|
| CAS Number | 640-68-6 |
| Molecular Formula | C5H11NO2 |
| Molecular Weight | 117.15 g/mol |
| Assay (HPLC) | 98.5% to 101.0% |
| Specific Rotation | -26.5° to -29.0° (c=8, 6M-HCl) |
| L-Isomer Impurity | Not more than 0.5% |
| Loss on Drying | Not more than 0.3% |
| Residue on Ignition | Not more than 0.1% |
| Heavy Metals (as Pb) | Not more than 10 ppm |
| Appearance | White crystalline powder |
Industrial Applications
The primary utility of D-Valine lies in its function as a chiral pool source for organic synthesis. It is extensively employed in the preparation of pharmaceutical intermediates, where stereochemistry is critical for biological activity. In the peptide industry, it acts as a fundamental building block for synthesizing specific peptide sequences that require D-amino acid residues to enhance metabolic stability or alter biological conformation.
Furthermore, this compound is utilized in the development of specialized agrochemicals and serves as a precursor for various fine chemical transformations. Its role as a chiral auxiliary allows chemists to induce asymmetry in subsequent reaction steps, facilitating the production of single-enantiomer compounds. The versatility of D-Valine makes it a staple ingredient in laboratories focused on medicinal chemistry and process development.
Quality Assurance and Storage
Every batch undergoes comprehensive analytical testing, including HPLC, polarimetry, and loss on drying analysis, to verify compliance with established specifications. A Certificate of Analysis (COA) is provided with each shipment to document quality metrics. For optimal preservation, the product should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly sealed to prevent moisture absorption, which could affect flowability and purity over time. Proper handling ensures the material retains its integrity throughout the supply chain.
