Peptides & Building Blocks

Eptifibatide

CAS No.148031-34-9
GradeIndustrial / Pharmaceutical
Availability● In Stock

High-purity Eptifibatide (CAS 148031-34-9), a clinically validated antiplatelet peptide used in cardiovascular interventions. Supplied as white to off-white powder with ≥98.0% assay.

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Product Technical Details

Product Overview

Eptifibatide is a synthetic cyclic heptapeptide that functions as a selective, reversible antagonist of the glycoprotein (GP) IIb/IIIa receptor on human platelets. As an arginine-glycine-aspartic acid (RGD) mimetic, it inhibits platelet aggregation by blocking the final common pathway of platelet cross-linking, making it a critical therapeutic agent in acute coronary syndromes and percutaneous coronary interventions.

Specifications

Molecular Formula	C₃₅H₄₉N₁₁O₉S₂
Molecular Weight	831.962 g/mol
CAS Number	148031-34-9
Appearance	White to off-white powder
Assay (HPLC)	≥98.0%
Melting Point	92–98 °C
Density	1.6 ± 0.1 g/cm³
Refractive Index	1.735

Industrial Applications

Eptifibatide is exclusively employed in advanced pharmaceutical formulations for cardiovascular care. It is indicated as an adjunct to heparin and aspirin in patients with unstable angina or non-ST-segment elevation myocardial infarction (NSTEMI) undergoing percutaneous coronary intervention (PCI), including angioplasty and stent placement. Its rapid onset and short half-life allow for precise control of antithrombotic therapy during high-risk cardiac procedures.

Validated for use in injectable antiplatelet regimens under strict clinical protocols
Serves as a key active pharmaceutical ingredient (API) in hospital-based acute care settings
Manufactured under cGMP conditions to meet stringent regulatory standards for parenteral therapeutics

Storage: Store in a cool, dry, and well-ventilated area away from direct light. Packaging: Standard 25 kg fiber drums with double-layer polyethylene liners; custom packaging available upon request.