Peptides & Building Blocks

Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate

  • CAS No.137156-41-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate serves as an efficient condensation reagent for peptide synthesis, ensuring minimal racemization and superior coupling yields.

Request a Quote & Full COA

Product Technical Details

Product Overview

Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate, commonly known as HOCT, is a specialized heterocyclic compound widely utilized in advanced organic synthesis and pharmaceutical manufacturing. As a derivative of hydroxytriazole, this chemical functions primarily as a potent condensation reagent and additive in peptide coupling reactions. Its unique molecular structure allows it to significantly enhance reaction efficiency while suppressing unwanted racemization processes, making it indispensable for the production of high-quality peptide-based therapeutics and research materials.

Our manufacturing facility adheres to strict quality control protocols to ensure every batch meets rigorous international standards. This product is designed for industrial-scale applications where consistency and purity are paramount. By integrating this reagent into your synthesis workflow, laboratories can achieve improved yields and reduced side reactions, ultimately optimizing the overall production timeline for complex molecular structures.

Key Specifications

ParameterSpecification
Chemical NameEthyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate
CAS Number137156-41-3
Molecular FormulaC5H7N3O3
Molecular Weight157.13 g/mol
AppearanceWhite crystal
Purity (HPLC)≥99.0%
Density1.49 g/cm3
Boiling Point339.117oC
Flash Point158-892oC
Refractive Index1.602

Industrial Applications

The primary application of Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate lies in the field of peptide synthesis. It acts as a crucial additive during the activation of carboxylic acids, facilitating the formation of peptide bonds with high fidelity. Unlike traditional reagents, HOCT offers superior stability and solubility profiles, which are essential for maintaining reaction homogeneity in various solvent systems. This capability is particularly valuable in the development of novel pharmaceutical APIs and biochemical research tools.

Beyond peptide coupling, this compound serves as a versatile intermediate in the synthesis of other heterocyclic derivatives. Its reactivity profile allows chemists to explore diverse synthetic routes for creating complex organic molecules. Whether used in academic research or large-scale industrial production, the reliability of this reagent ensures consistent outcomes across different batches and processes.

Why Choose Our HOCT

  • Exceptional Purity: Guaranteed ≥99.0% purity via HPLC analysis to minimize impurities.
  • Technical Support: Dedicated team available to assist with synthesis optimization and troubleshooting.
  • Global Logistics: Secure packaging and reliable shipping methods to ensure product integrity upon arrival.
  • Custom Packaging: Flexible options including 25 kg drums or tailored solutions based on specific project requirements.
  • Regulatory Compliance: Manufactured in facilities adhering to strict safety and environmental standards.

Storage and Handling

To maintain optimal quality, store this product in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures should be followed according to safety data sheets. The material is classified under Hazard Class 8 with UN Number 2735, requiring appropriate precautions during transport and storage. By following these guidelines, users can ensure the longevity and performance of the reagent in their specific applications.