Fmoc-4-Chloro-D-Phe-OH

Product Overview

Fmoc-4-Chloro-D-Phe-OH is a specialized protected amino acid derivative essential for modern solid-phase peptide synthesis. This compound features a fluorenylmethoxycarbonyl protecting group on the amine function and a chlorine substitution at the para position of the phenyl ring. The D-configuration provides specific stereochemical properties required for constructing biologically active peptides with enhanced stability or unique receptor binding profiles. Our manufacturing process ensures consistent quality suitable for pharmaceutical research and development.

Chemical Properties and Specifications

The molecular structure combines robust chemical stability with high reactivity during coupling reactions. The Fmoc group allows for mild deprotection conditions using secondary amines, preserving acid-sensitive side chains. The 4-chloro substitution modifies the electronic properties of the aromatic ring, influencing the hydrophobicity and conformational behavior of the final peptide sequence. Rigorous quality control measures are implemented at every stage of production to meet international standards.

Industrial Applications

This building block is primarily utilized in the synthesis of complex peptide therapeutics and research compounds. The D-phenylalanine derivative is crucial for creating peptides resistant to enzymatic degradation, thereby extending half-life in biological systems. It serves as a key intermediate in the development of novel drug candidates where specific stereochemistry is required for target engagement. Researchers value this material for its reliability in automated synthesizers and manual coupling protocols.

Quality Assurance and Storage

We maintain strict quality management systems to ensure every batch meets specified criteria. Each shipment includes a Certificate of Analysis detailing purity, optical rotation, and physical constants. Proper storage is critical to maintain stability over time. The product should be kept in a tightly closed container in a cool, dry place away from direct light. Recommended storage temperatures range between 2 to 8 degrees Celsius to prevent degradation of the Fmoc group. Long-term stability is ensured through proper packaging and handling procedures during transit.

Why Choose Our Supply

• Consistent high purity levels exceeding 99 percent
• Comprehensive documentation including COA and MSDS
• Scalable production capacity for bulk requirements
• Global logistics network for timely delivery
• Dedicated technical support for synthesis optimization

Our commitment to excellence makes us a preferred partner for laboratories and manufacturing facilities worldwide. We understand the critical nature of raw materials in peptide development and strive to provide unmatched reliability and service.