Fmoc-Cys(Acm)-OH

Product Overview

Fmoc-Cys(Acm)-OH represents a critical building block in the realm of modern peptide chemistry and pharmaceutical development. As a protected derivative of L-cysteine, this compound features the fluorenylmethoxycarbonyl (Fmoc) group on the alpha-amino function and the acetamidomethyl (Acm) group on the sulfhydryl side chain. This dual protection strategy is specifically designed to facilitate solid-phase peptide synthesis (SPPS) while preventing unwanted side reactions such as disulfide bond formation during the assembly process. Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for research laboratories and industrial production facilities alike.

Technical Specifications

We maintain strict quality control protocols to guarantee the performance of our chemical intermediates. The following table outlines the key physical and chemical properties associated with this product. These specifications are verified through advanced analytical techniques including HPLC and NMR spectroscopy to ensure reliability for your synthesis projects.

Quality Assurance and Storage

Maintaining the integrity of protected amino acids is paramount for successful peptide synthesis. Fmoc-Cys(Acm)-OH is sensitive to moisture and elevated temperatures, which can lead to premature deprotection or degradation. Therefore, we recommend storing this material in a cool, dry environment between 2 and 8 degrees Celsius. Containers should remain tightly closed when not in use to prevent exposure to atmospheric humidity. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) that details the specific batch data, including purity levels and impurity profiles. Our commitment to quality ensures that researchers can rely on consistent results across multiple production runs.

Industrial Applications

This protected amino acid finds extensive use in the synthesis of complex peptides and protein therapeutics. The Acm protecting group is particularly valuable because it is stable under the acidic conditions used to remove the Fmoc group, yet it can be selectively removed later to allow for specific disulfide bridge formation. Key applications include:

• Solid-phase peptide synthesis (SPPS) for pharmaceutical drug development.
• Production of hormonal peptides and bioactive compounds.
• Research into novel protein structures and folding mechanisms.
• Custom peptide manufacturing for diagnostic and therapeutic purposes.

Global Supply and Logistics

As a established manufacturer in the fine chemicals sector, we understand the importance of timely delivery and secure packaging. Our products are packaged in durable drums suitable for international shipping, with options available for custom quantities based on client requirements. We adhere to all relevant safety regulations for the transport of chemical materials. Whether you require small-scale quantities for laboratory research or bulk volumes for commercial manufacturing, our supply chain is optimized to meet your demands efficiently. Contact our technical sales team today to discuss your specific project needs and request a competitive quote for Fmoc-Cys(Acm)-OH.