Fmoc-D-Cys(phacm)

Product Overview

Fmoc-D-Cys(phacm) represents a critical specialized reagent within the realm of advanced peptide chemistry. As a protected derivative of D-Cysteine, this compound features both Fmoc (9-Fluorenylmethoxycarbonyl) protection on the amine group and a Phacm (phenylacetylaminomethyl) group on the sulfur atom. This dual protection strategy is essential for preventing unwanted side reactions during complex solid-phase peptide synthesis (SPPS) processes. Our manufacturing facility ensures that every batch meets rigorous international standards for pharmaceutical intermediates, providing researchers and production teams with reliable materials for drug discovery and development.

Technical Specifications

We maintain strict quality control protocols to guarantee the consistency and purity of our chemical building blocks. The following table outlines the key physical and chemical properties verified through our analytical laboratories.

Industrial Applications

This protected amino acid is primarily utilized in the synthesis of therapeutic peptides and peptidomimetics. The D-configuration offers unique structural properties that can enhance metabolic stability or modify receptor binding affinity in final drug candidates. Key application areas include:

• Solid-phase peptide synthesis (SPPS) as a reliable building block.
• Development of novel pharmaceutical APIs requiring cysteine modifications.
• Research into protease inhibitors and enzyme substrates.
• Creation of cyclic peptides where disulfide bridge formation must be controlled.

Quality Assurance and Storage

As a global manufacturer, we provide comprehensive documentation including Certificates of Analysis (COA) for every shipment. Our products are packaged in secure 25 kg drums or customized containers based on client requirements to ensure integrity during transit. For optimal stability, store the container tightly closed in a cool, dry place away from direct sunlight and moisture. Proper storage conditions maintain the chemical integrity of the Fmoc and Phacm protecting groups, ensuring high yields in downstream synthesis reactions. Contact our technical sales team for bulk pricing, custom synthesis options, and detailed manufacturing process information.