Peptides & Building Blocks

Fmoc-L-Alaninol

  • CAS No.161529-13-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Fmoc-L-Alaninol (CAS 161529-13-1) is a premium chiral building block designed for efficient peptide synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

Fmoc-L-Alaninol, identified by CAS number 161529-13-1, stands as a critical chiral building block within the realm of modern organic synthesis and peptide chemistry. As a protected amino alcohol, this compound features the 9-fluorenylmethoxycarbonyl (Fmoc) group, which is renowned for its stability under acidic conditions and ease of removal under mild basic conditions. This specific protection strategy makes it an indispensable reagent for solid-phase peptide synthesis (SPPS) and the construction of complex pharmaceutical intermediates.

Our manufacturing process ensures that every batch meets rigorous international standards for optical purity and chemical integrity. The compound serves as a versatile precursor for introducing the alaninol moiety into various molecular structures, facilitating the development of novel therapeutic agents and biochemical research tools.

Technical Specifications

ParameterSpecification
Chemical NameFmoc-L-Alaninol
CAS Number161529-13-1
Molecular FormulaC18H19NO3
Molecular Weight297.35 g/mol
Purity≥98.0%
AppearanceWhite or Off-white Powder
Optical RotationConsistent with L-Configuration

Industrial Applications

The primary application of Fmoc-L-Alaninol lies in the pharmaceutical and biotechnology sectors. It is extensively utilized in the synthesis of peptide-based drugs, where stereochemical purity is paramount for biological activity. Researchers and process chemists rely on this building block to construct specific sequences that mimic natural peptides or create entirely new pharmacophores.

Beyond peptide synthesis, this compound finds utility in the preparation of heterocyclic compounds and other fine chemicals. Its hydroxyl group offers additional functionality for further derivatization, allowing chemists to create diverse libraries of compounds for drug discovery programs. The high stability of the Fmoc group ensures that the integrity of the molecule is maintained throughout multi-step synthesis routes.

Quality Assurance and Advantages

  • High Optical Purity: Ensures minimal racemization during synthesis.
  • Strict QC Protocols: Every batch is tested using HPLC and NMR.
  • Consistent Supply: Robust manufacturing capacity for bulk orders.
  • Documentation: Full COA and MSDS provided with shipment.

Storage and Handling

To maintain optimal quality, Fmoc-L-Alaninol should be stored in a cool, dry environment, ideally at temperatures below -15ºC for long-term stability. The container must remain tightly closed to prevent moisture absorption, which could affect the reactivity of the hydroxyl group. When handling, standard laboratory safety precautions should be observed, including the use of appropriate personal protective equipment. We offer flexible packaging options, including 25 kg drums, customized to meet specific logistical requirements for global shipping.