Fmoc-L-Phenylalanine
- CAS No.35661-40-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Fmoc-L-Phenylalanine is a high-purity protected amino acid essential for solid-phase peptide synthesis. Our grade ensures superior chiral integrity and reaction efficiency.
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Product Overview
Fmoc-L-Phenylalanine is a critically important N-protected amino acid derivative widely utilized in the field of organic synthesis and pharmaceutical development. As a key building block, it features the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, which is specifically designed for base-labile deprotection strategies. This chemical structure allows for efficient incorporation into growing peptide chains during solid-phase peptide synthesis (SPPS) without compromising the stereochemical integrity of the phenylalanine residue.
Our manufacturing process ensures that each batch meets rigorous international standards for purity and chiral stability. The compound is supplied as a white crystalline powder, characterized by its excellent solubility in common organic solvents such as dimethylformamide (DMF) and dichloromethane. This physical property facilitates smooth coupling reactions, minimizing racemization risks that could otherwise affect the biological activity of the final peptide product.
Key Specifications
| Parameter | Specification |
|---|---|
| Appearance | White powder |
| Moisture Content | ≤1.0% |
| Melting Point | 78.0~87.0℃ |
| Chiral Purity | ≥99.0% |
| Chemical Purity | ≥98.5% |
Industrial Applications
This protected amino acid serves as a fundamental reagent in the construction of complex peptide structures. Its primary application lies in the pharmaceutical industry, where it is used to synthesize therapeutic peptides and protein fragments. Additionally, it is valuable in biochemical research for creating custom peptides used in enzyme assays and receptor binding studies. The high chiral purity guarantees that the synthesized peptides maintain their intended conformation and biological function.
- Solid-phase peptide synthesis (SPPS)
- Solution-phase peptide coupling
- Development of peptide-based pharmaceuticals
- Biochemical research reagents
Quality Assurance and Storage
Quality control is paramount in the production of fine chemical intermediates. Each lot of Fmoc-L-Phenylalanine undergoes comprehensive analysis, including HPLC for purity verification and polarimetry for chiral assessment. We provide a Certificate of Analysis (COA) with every shipment to ensure transparency and compliance with your internal quality protocols. To maintain stability, the product should be stored in a cool, dry environment at temperatures between 2-8°C. Under these conditions, the material remains stable under normal pressures, ensuring a long shelf life for your inventory. We are committed to supplying global manufacturers with consistent quality, competitive bulk pricing, and reliable logistics support.
