Fmoc-N-methyl-D-phenylalanine

Product Overview

Fmoc-N-methyl-D-phenylalanine is a specialized protected amino acid derivative essential for modern pharmaceutical research and development. Identified by CAS number 138775-05-0, this compound serves as a critical building block in the construction of complex peptide sequences. The incorporation of an N-methyl group alongside the D-stereochemistry provides unique conformational constraints, enhancing metabolic stability and bioavailability in final therapeutic candidates. Our manufacturing process ensures consistent quality suitable for demanding solid-phase peptide synthesis (SPPS) applications.

Technical Specifications

We adhere to strict quality control protocols to guarantee the integrity of every batch. The physical and chemical properties are meticulously verified to meet international standards for research-grade and industrial-grade materials. Below are the key technical parameters associated with this product.

Industrial Applications

This Fmoc-protected derivative is primarily utilized in the synthesis of bioactive peptides and peptidomimetics. The N-methylation strategy is particularly valuable for reducing enzymatic degradation and improving membrane permeability in drug design. Researchers leverage this building block to introduce steric hindrance and modify the secondary structure of peptide chains. It is compatible with standard Fmoc chemistry protocols, ensuring smooth coupling reactions without significant racemization. Common use cases include the development of neurological therapeutics, oncology targets, and advanced diagnostic agents.

Quality Assurance And Packaging

As a global manufacturer, we prioritize safety and reliability throughout the supply chain. Each production lot undergoes rigorous testing using HPLC and NMR spectroscopy to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with every shipment to facilitate regulatory compliance and quality verification. The product is packaged in secure 25kg drums, though custom packaging solutions are available to meet specific logistical requirements. Proper storage in a cool, dry, and well-ventilated environment is recommended to maintain stability over extended periods. We invite partners to contact our technical team for detailed specifications, bulk pricing inquiries, and sample requests.