Peptides & Building Blocks

Fmoc-N-methyl-L-phenylalanine

  • CAS No.77128-73-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Fmoc-N-methyl-L-phenylalanine for advanced peptide synthesis. Reliable supply with full documentation and competitive bulk pricing.

Request a Quote & Full COA

Product Technical Details

Product Overview

Fmoc-N-methyl-L-phenylalanine is a highly specialized protected amino acid derivative designed for use in solid-phase peptide synthesis (SPPS). As a crucial building block in modern pharmaceutical research, this compound features an N-methylated phenylalanine backbone protected by the Fluorenylmethyloxycarbonyl (Fmoc) group. This specific structural configuration enhances metabolic stability and modifies the conformational properties of resulting peptides, making it invaluable for developing novel therapeutic agents and biological probes.

Our manufacturing process ensures exceptional chemical integrity and consistency. Each batch undergoes rigorous quality control testing to meet stringent industry standards. The N-methylation process introduces steric hindrance that can prevent enzymatic degradation, thereby improving the pharmacokinetic profile of synthesized peptides. This makes the compound particularly suitable for research into complex biological systems and potential pharmaceutical applications.

Technical Specifications

ParameterValue
CAS Number77128-73-5
Molecular FormulaC25H23NO4
Molecular Weight401.454
AppearanceWhite powder
Assay≥98.0%
Density1.3±0.1 g/cm3
Boiling Point595.4±39.0 °C at 760 mmHg
Flash Point313.9±27.1 °C
Storage Condition2-8°C

Applications and Benefits

This compound serves as a critical intermediate in the synthesis of bioactive peptides. It is extensively used in the pharmaceutical industry for creating peptide inhibitors and modifying peptide structures to enhance stability. Research applications include studies on parasitic inhibitors and other advanced neurological therapeutics where peptide stability is paramount. The Fmoc protection group allows for orthogonal deprotection strategies, facilitating the synthesis of complex sequences without affecting other sensitive functional groups within the molecule.

  • Enhanced metabolic stability due to N-methylation.
  • Compatible with standard Fmoc solid-phase peptide synthesis protocols.
  • High purity ensures minimal side reactions during coupling.
  • Ideal for developing peptide-based pharmaceutical intermediates.
  • Supports research into advanced organic synthesis and drug discovery.

Quality Assurance and Storage

We maintain a robust quality management system to guarantee product reliability. Certificate of Analysis (COA) documents are provided with every shipment, detailing batch-specific test results including purity, identity, and physical properties. To maintain optimal stability, the product should be stored in a cool place, ideally between 2 to 8 degrees Celsius. Containers must be kept tightly closed in a dry and well-ventilated environment to prevent moisture absorption and degradation. Proper handling ensures the material retains its specified characteristics throughout its shelf life.

Packaging and Logistics

Standard packaging is available in 25kg drums, suitable for industrial scale operations. We also offer customized packaging solutions based on specific customer requirements and logistical needs. As a global manufacturer, we ensure secure packaging to prevent damage during transit. Our supply chain is optimized for timely delivery worldwide, supporting both research laboratories and large-scale production facilities. Contact our sales team for detailed information on bulk pricing and shipping options tailored to your region.