Fmoc-L-Octahydroindole-2-Carboxylic Acid

Product Overview

Fmoc-L-Octahydroindole-2-Carboxylic Acid, commonly referred to as Fmoc-Oic-OH, is a specialized non-natural amino acid derivative essential for modern peptide chemistry. As a rigidified proline analog, this building block introduces conformational constraints into peptide chains, significantly enhancing metabolic stability and biological activity of the final therapeutic candidates. Our manufacturing process ensures superior stereochemical integrity, making it an ideal choice for complex drug discovery programs.

Key Specifications

Industrial Applications

This compound serves as a critical intermediate in the solid-phase peptide synthesis (SPPS) of bioactive peptides and peptidomimetics. The octahydroindole scaffold provides unique structural rigidity, which is particularly valuable in the development of protease inhibitors and receptor antagonists. Researchers utilize Fmoc-Oic-OH to improve the pharmacokinetic profiles of lead compounds by reducing enzymatic degradation.

Quality Assurance

• Strict control over chiral purity to minimize D-enantiomer contamination.
• Comprehensive testing via HPLC, TLC, and specific rotation analysis.
• Low water content and loss on drying ensure stability during storage.
• Full documentation including Certificate of Analysis (COA) provided with every batch.

Our facility adheres to rigorous quality management systems to guarantee batch-to-batch consistency. We support global clients with reliable supply chains, competitive bulk pricing, and technical support for scale-up processes. For detailed specifications or custom synthesis inquiries, please contact our sales team directly.