Ghrelin (Rat)
- CAS No.258338-12-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity Ghrelin (Rat) peptide for advanced research applications. Validates growth hormone release and energy regulation mechanisms in preclinical models.
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Product Overview
Ghrelin (Rat) is a highly specialized bioactive peptide hormone synthesized for advanced pharmaceutical and life science research. As an endogenous agonist for the growth hormone secretagogue receptor (GHS-R1a), this compound plays a pivotal role in understanding metabolic regulation, feeding behavior, and energy homeostasis. Our manufacturing process ensures exceptional purity and structural integrity, making it an ideal candidate for rigorous in vitro and in vivo studies.
This peptide is primarily produced in the stomach and acts as a potent signaling molecule within the neuroendocrine system. Researchers utilize this specific rat sequence to investigate species-specific physiological responses that may differ from human analogs. By providing a reliable source of high-quality Ghrelin (Rat), we support the development of novel therapeutic strategies targeting metabolic disorders and growth-related conditions.
Mechanism of Action
The biological activity of Ghrelin (Rat) is mediated through its binding affinity to the GHS-R1a receptor. Upon binding, it triggers a cascade of intracellular signaling pathways that stimulate the release of growth hormone from the pituitary gland. This mechanism is critical for regulating body composition, bone density, and muscle mass. Furthermore, Ghrelin influences appetite signaling in the hypothalamus, making it a key subject of study for energy balance and obesity research.
Understanding these pathways requires reagents with consistent potency and minimal impurities. Our production standards adhere to strict quality control protocols to ensure that every batch performs reliably in complex biological assays. This consistency is essential for reproducing experimental results and validating hypotheses in academic and industrial settings.
Industrial Applications
Ghrelin (Rat) serves as a fundamental tool in various research domains, including endocrinology, neuroscience, and pharmacology. Common applications include:
- Investigation of growth hormone secretion dynamics in rodent models.
- Studies on appetite regulation and feeding behavior mechanisms.
- Research into energy expenditure and metabolic rate modulation.
- Development of potential therapeutics for cachexia and wasting syndromes.
- Exploration of neuroprotective effects and cognitive function links.
These applications highlight the versatility of this peptide as a research tool. Whether used for binding assays, cell culture stimulation, or animal studies, the quality of the starting material directly impacts the validity of the scientific outcomes.
Quality Specifications
We maintain rigorous quality assurance measures to guarantee the performance of our peptides. Each batch undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and mass spectrometry (MS). The following table outlines the standard specifications for this product:
| Parameter | Specification |
|---|---|
| CAS Number | 258338-12-4 |
| Molecular Formula | C147H245N45O42 |
| Molecular Weight | 3314.794 |
| Appearance | White to off-white powder |
| Purity (Assay) | ≥98.0% |
| Density | 1.5±0.1 g/cm3 |
| Refractive Index | 1.667 |
Storage and Handling
To maintain stability and biological activity, proper storage conditions are essential. Ghrelin (Rat) should be stored in a cool, ventilated place away from direct sunlight and moisture. Long-term storage is recommended at low temperatures to prevent degradation. Users should handle the material with appropriate personal protective equipment and follow standard laboratory safety guidelines. For extended shelf life, reconstitution should be performed immediately prior to use with sterile buffers.
We offer flexible packaging options, including 25 kg drums or customized quantities based on project requirements. Our global logistics network ensures timely delivery while maintaining cold chain integrity where necessary. Contact our technical team for detailed handling instructions and certificate of analysis (COA) documentation.
