Glucagon-Like Peptide-1 (7-36), Amide, Human

Product Overview

Glucagon-Like Peptide-1 (7-36), amide, human is a biologically active fragment of the endogenous incretin hormone GLP-1. This peptide plays a pivotal role in glucose homeostasis by enhancing glucose-dependent insulin secretion from pancreatic beta cells while simultaneously suppressing glucagon release and delaying gastric emptying. Synthesized to stringent pharmaceutical standards, it serves as a critical tool in metabolic disorder research and the development of next-generation therapeutics.

Specifications

Industrial Applications

This high-purity peptide is primarily utilized in preclinical and clinical research settings focused on type 2 diabetes, obesity, and related metabolic syndromes. Its well-characterized biological activity makes it an ideal reference standard or active component in formulation studies aimed at developing stable, long-acting GLP-1 receptor agonists. Researchers leverage this material for:

• In vitro and in vivo studies of insulinotropic mechanisms
• Structure-activity relationship (SAR) analyses of incretin mimetics
• Development of biosimilar or novel peptide-based therapeutics
• Performance benchmarking against existing GLP-1 analogs

As a functional building block with defined physiological effects, it supports innovation in advanced organic synthesis and neurological therapeutics without involvement in any controlled or restricted substances.