Peptides & Building Blocks

L-Alanine Methyl Ester Hydrochloride

  • CAS No.2491-20-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity L-Alanine Methyl Ester Hydrochloride designed for peptide synthesis and pharmaceutical research. Available in bulk with full documentation.

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Product Technical Details

Product Overview

L-Alanine Methyl Ester Hydrochloride is a premium chiral building block extensively utilized in the pharmaceutical and biotechnology sectors. As the hydrochloride salt of the methyl ester of L-Alanine, this compound offers enhanced stability and solubility, making it an ideal reagent for organic synthesis. Our manufacturing process adheres to strict quality control standards to ensure consistent stereochemical purity, specifically maintaining the S-configuration essential for biological activity in downstream applications.

This chemical serves as a fundamental component in the construction of complex peptide chains. The methyl ester protection group allows for selective reactions during solid-phase peptide synthesis (SPPS) and solution-phase coupling. By preserving the chiral integrity of the alanine backbone, researchers and manufacturers can achieve high yields and minimize racemization risks during multi-step synthesis routes.

Technical Specifications

ParameterSpecification
CAS Number2491-20-5
Molecular FormulaC4H10ClNO2
Molecular Weight139.58 g/mol
AppearanceWhite Crystalline Powder
Purity (HPLC)≥98.0%
Melting Point109-111 °C
Optical Rotation+6.5° (C=2, MeOH)
Loss on Drying≤0.5%

Industrial Applications

The primary application of this compound lies in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is frequently employed in the production of peptide-based therapeutics, where amino acid esters act as crucial coupling partners. Additionally, this material is valuable in metabolic research, serving as a reference standard for studying alanine pathways and glucose metabolism in clinical studies.

  • Peptide Drug Development: Essential building block for constructing therapeutic peptides.
  • Organic Synthesis: Used as a chiral pool material for asymmetric synthesis.
  • Research Reagent: Utilized in biochemical assays and metabolic profiling.
  • Agrochemical Intermediates: Applied in the synthesis of specific herbicide and pesticide derivatives.

Quality Assurance and Storage

Every batch of L-Alanine Methyl Ester Hydrochloride undergoes rigorous testing using High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy. We provide a comprehensive Certificate of Analysis (COA) with each shipment to verify compliance with specified purity levels and impurity profiles. Our facility operates under Good Manufacturing Practice (GMP) guidelines to ensure product safety and traceability.

For optimal stability, this product should be stored in a cool, dry environment at temperatures below -20°C. Containers must remain tightly sealed to prevent moisture absorption, which could lead to hydrolysis of the ester group. We offer flexible packaging options, including 25 kg drums, and can customize packaging solutions to meet specific logistical requirements for global export.