Peptides & Building Blocks

L-Cystine bis(t-butyl ester) dihydrochloride

  • CAS No.38261-78-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity protected amino acid derivative designed for advanced peptide synthesis and pharmaceutical intermediate applications.

Request a Quote & Full COA

Product Technical Details

Product Overview

L-Cystine bis(t-butyl ester) dihydrochloride represents a critical protected amino acid derivative utilized extensively in the field of modern peptide chemistry. This compound features a cystine backbone where both carboxylic acid groups are protected as tert-butyl esters, providing enhanced stability during complex synthetic sequences. The dihydrochloride salt form ensures improved solubility and handling characteristics suitable for large-scale pharmaceutical manufacturing processes.

As a key building block, this molecule allows chemists to incorporate cystine residues into peptide chains while preventing unwanted side reactions at the carboxyl termini. The robust tert-butyl protection group is stable under various conditions yet can be selectively removed when necessary, offering flexibility in multi-step synthesis routes.

Chemical Properties and Specifications

Our manufacturing process adheres to strict quality control protocols to ensure consistent batch-to-batch reliability. The product is supplied as a fine white powder with high optical purity, maintaining the stereochemical integrity required for bioactive peptide production. Below are the key technical specifications for this material.

ParameterSpecification
Chemical NameL-Cystine bis(t-butyl ester) dihydrochloride
CAS Number38261-78-8
Molecular FormulaC14H30Cl2N2O4S2
Molecular Weight425.44 g/mol
AppearanceWhite powder
Purity≥98.0%
Storage Temperature-15°C

Industrial Applications

This protected amino acid is primarily employed as a pharmaceutical intermediate in the synthesis of complex peptides and protein therapeutics. The disulfide bridge inherent in the cystine structure is vital for stabilizing the three-dimensional conformation of many biologically active peptides. By using this bis-esterified form, manufacturers can streamline production workflows and reduce purification burdens.

  • Solid-phase peptide synthesis (SPPS) building block
  • Production of hormonal therapeutics and enzymes
  • Research and development of novel peptide drugs
  • Custom synthesis for academic and industrial laboratories

Storage and Handling Guidelines

To maintain optimal quality, proper storage conditions are essential. This compound should be kept at -15°C in a tightly sealed container to prevent moisture absorption and degradation. The material is hygroscopic and sensitive to prolonged exposure to ambient humidity. Always handle in a well-ventilated area using appropriate personal protective equipment. For long-term stability, ensure the packaging remains intact until ready for use.

Quality Assurance and Supply

We operate as a global manufacturer committed to delivering high-quality chemical solutions. Every batch undergoes rigorous testing using advanced analytical methods such as HPLC and NMR to verify identity and purity. Comprehensive Certificates of Analysis (COA) are provided with each shipment. Our supply chain is optimized for reliability, ensuring timely delivery of bulk quantities to support your production schedules without interruption.