L-Homophenylalanine
- CAS No.943-73-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade L-Homophenylalanine suitable for peptide synthesis and pharmaceutical intermediates. High optical purity and assay guaranteed.
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Product Overview
L-Homophenylalanine is a specialized non-proteinogenic amino acid derivative that serves as a critical building block in the pharmaceutical and biotechnology sectors. Known chemically as (2S)-2-amino-4-phenylbutanoic acid, this compound features a unique homophenyl structure that distinguishes it from standard phenylalanine. Our manufacturing process ensures high optical purity and consistent quality, making it an ideal candidate for complex organic synthesis and peptide chain elongation. As a leading supplier in the fine chemicals industry, we understand the stringent requirements for pharmaceutical intermediates and deliver materials that meet global regulatory expectations.
This product is extensively utilized in the development of angiotensin-converting enzyme inhibitors and other therapeutic peptides. The extended side chain provides specific steric and electronic properties required for high-affinity binding in biological systems. Our facility employs advanced crystallization techniques to ensure superior physical properties, including consistent particle size and excellent solubility profiles suitable for various reaction conditions.
Technical Specifications
Quality control is paramount in our production facility. Each batch undergoes rigorous testing using high-performance liquid chromatography and polarimetry to ensure compliance with international standards. The following table outlines the key physical and chemical parameters guaranteed for our commercial grade material. We maintain full traceability for all raw materials used in the synthesis process.
| Parameter | Specification |
|---|---|
| Solubility in Water | Colorless and Clear (c=1) |
| Specific Rotation [α]D20 | +43.3° to +47.0° (c=1, 3M-HCl) |
| Assay (HPLC) | 98.5% to 101.0% |
Industrial Applications
The versatility of L-Homophenylalanine allows for its integration into various synthetic routes within the medicinal chemistry landscape. Primary applications include the synthesis of antihypertensive pharmaceutical agents where stereochemistry plays a vital role in efficacy. It is also used for the construction of bioactive peptide sequences and research and development of novel protease inhibitors. Additionally, it serves as a chiral pool component in asymmetric synthesis for creating complex molecular architectures.
- Synthesis of antihypertensive pharmaceutical agents.
- Construction of bioactive peptide sequences.
- Research and development of novel protease inhibitors.
- Use as a chiral pool component in asymmetric synthesis.
Quality Assurance and Storage
We maintain a robust quality management system to track every production lot from raw material sourcing to final packaging. Certificates of Analysis are provided with every shipment to verify identity and purity. To maintain stability, the product should be stored in a cool, dry place away from direct sunlight and moisture. Proper sealing is recommended to prevent hydration or contamination during long-term storage. Our commitment to excellence ensures that clients receive materials that meet the highest standards of purity and performance. For custom packaging or large-scale procurement inquiries, our technical sales team is available to provide detailed support and logistics solutions globally.
