(4S)-4-Propan-2-yl-1,3-oxazolidine-2,5-dione

Product Overview

The compound (4S)-4-propan-2-yl-1,3-oxazolidine-2,5-dione, commonly known as L-Valine N-carboxyanhydride (Valine NCA), represents a critical building block in the field of polypeptide synthesis and advanced pharmaceutical manufacturing. As a protected amino acid derivative, this substance enables the ring-opening polymerization process essential for creating defined peptide sequences and biomimetic materials. Our production facility adheres to strict quality control protocols to ensure high stereochemical purity, specifically maintaining the (4S) configuration which is vital for biological activity and downstream reaction efficiency.

From a chemical stability perspective, the oxazolidinedione ring structure is highly reactive towards nucleophiles, which is the fundamental mechanism exploited in polymerization reactions. However, this reactivity necessitates careful exclusion of ambient humidity during handling. Our packaging utilizes moisture-barrier materials to protect the integrity of the product during transit. Safety data sheets are available upon request, outlining appropriate personal protective equipment and emergency measures for industrial handling.

Technical Specifications

We maintain rigorous standards for all chemical parameters to ensure consistency across batches. The following table outlines the key physical and chemical properties verified during our quality assurance process.

Applications and Benefits

In the context of industrial applications, this NCA derivative serves as a precursor for synthesizing poly(valine) and various copolymers used in drug delivery systems and tissue engineering scaffolds. The high purity grade we offer minimizes side reactions during polymerization, ensuring consistent molecular weight distribution and optimal material properties. Researchers and manufacturers rely on this intermediate for developing novel therapeutic peptides and functionalized biomaterials that require precise structural control.

• High stereochemical purity ensures biological compatibility.
• Low moisture and chloride content prevent premature hydrolysis.
• Suitable for large-scale polypeptide production.
• Verified by NMR and HPLC for structural accuracy.

Storage and Handling

The physical characteristics of this product include a white crystalline solid appearance with a melting point range of 70 to 71 degrees Celsius. Proper handling is essential due to the compound's sensitivity to moisture and heat. We recommend storage in tightly closed containers at low temperatures, ideally around zero degrees Celsius, to maintain stability over extended periods. Packaging options include 25 kg drums, with custom configurations available to suit specific logistical needs and production scales.

Quality Assurance

Our commitment to excellence extends beyond product quality to include comprehensive technical support. We provide Certificates of Analysis (COA) with every shipment, detailing test results against established standards. As a global manufacturer, we ensure reliable supply chains and competitive bulk pricing for partners engaged in large-scale peptide production. Whether for academic research or commercial manufacturing, our L-Valine NCA stands as a reliable choice for high-performance chemical synthesis.